AdvaClear by Metagenics is supposed to help you lose weight and improve overall health through balanced hepatic detoxification. It includes several vitamins and minerals, which are supposed to keep you healthy while your body is going through detoxification. Unfortunately, you cannot find enough evidence suggesting that this form of detoxification can help improve your overall health.
AdvaClear uses several ingredients and some of these ingredients work as laxatives. Milk thistle, for instance, has mild laxative effect. However, it is included in the blend mainly because it also provides you with antioxidants that are essential for the health of your liver and gallbladder. Antioxidants help eliminate free radicals from your body and improve your overall health. Many people use milk thistle to deal with alcoholic cirrhosis, but scientific studies have found contradictory results regarding the claims associated with milk thistle.
Some experts say that milk thistle is beneficial because it has a group of compounds called silymarin – these compounds are supposed to protect your liver against damage. However, these claims are not backed by many studies. Some studies with benefits of milk thistle have used very small number of participants, so you cannot always trust such studies.
In a 2007 review of 13 clinical trials, the independent Cochrane Collaboration questioned the use of milk thistle for alcoholic liver disease and hepatitis B and C because of the poor quality of the research. Moreover, nearly all studies have looked at milk thistle or silymarin in chronic liver disease; there’s little if any evidence the herb can ‘detoxify’ or protect a healthy liver, though this is what these supplements are typically marketed for.
What it implies is that milk thistle is usually ineffective, but whatever little results it produces are for those who already have unhealthy liver. If you are looking for a supplement to ‘detoxify’ your otherwise healthy liver, you may not notice any results from milk thistle. The same holds true for another ingredient found in AdvaClear – that is N-acetyl-L-Cysteine. It is naturally produced in your body and is required for the production of glutathione that works as an antioxidant in the body. Studies show that you may benefit from n-acetyl-l-cysteine only if you are already deficient in glutathione or are dealing with chronic liver inflammation.
There is also selenium in AdvaClear. It is an important mineral and offers many benefits, especially when combined with vitamin E, but it does nothing more than targeting free radicals in the body. It is not going to work if you are looking for a way to ‘detoxify’ your body quickly. Moreover, you should not expect any benefits if you are not already deficient in selenium. If you are taking a balanced diet or have while grains, shellfish, wheat germ, garlic, etc., in your diet, there is really no need to supplement with selenium. Even when you are deficient, you need to take up to 200 mcg a day. AdvaClear only provides you with 50 mcg per serving, which is certainly not going to make a lot of difference.
Watercress is also there and is supposed to work because it contains compounds called isothiocyanates. These compounds are supposed to protect you against carcinogens. However, there is limited human evidence suggesting that watercress may support liver health or your natural detoxification process. In terms of weight loss, watercress may help by eliminate excess water from your system because it acts as a natural laxative and diuretic. This is not weight loss in the real sense though.
The same is the case with artichoke extract, which is supposed to stimulate bile secretion and help with better fat digestion. The problem is that you need to take up to 6000 mg of the extract to notice any results. However, you may develop certain issues when you take high doses of artichoke extract because it also works as a laxative. Even when taken in larger doses, some studies have failed to notice significant results. For instance:
High dose (1,800 mg of a 25-35:1 concentrated extract) was associated with a reduction of liver enzymes and a betterment of some parameters, but not all.
Moreover, artichoke serves as a diuretic, which may help you lose some pounds, but it is easy to regain that water weight. Since it works as a diuretic, it is possible to experience some side effects. Therefore, you need to increase your intake of calories and water while you are taking artichoke, but that may make it difficult to lose weight.
How to Take AdvaClear
Take two capsules once daily or as directed by your healthcare practitioner.
Green tea catechins are beneficial but they may not make a significant difference to your body weight. Some studies show that green tea catechins can affect fat-burning pathways in a positive way, but that usually happens when you take up to 400-500 mg of EGCGs.
In a study done on obese persons with metabolic syndrome (mean BMI, 36.1), green tea provided in either drinks or capsules (totalling approximately 870-928 mg catechins daily, 440-460 mg EGCG) were given for 8 weeks. Subjects were not blinded to treatment, although their assessors were. Reductions in weight and biomarkers of oxidation were significant, 2.5+/-0.7 kg weight loss greater in the green tea groups. Trends were seen in reductions of triglycerides and LDL, and improvements in HDL; however, these were not statistically significant.
Unfortunately, you only get 56 mg of green tea extract from AdvaClear. Even in higher doses, there is an unreliable and insignificant increase in fat oxidation.
What it implies is that most of the ingredients found in AdvaClear are not going to ‘detoxify’ your body or improve your liver health significantly. Now, if you are looking for a way to help lose weight, AdvaClear is not going to impress you much. It includes nothing that would burn fat and help you eat fewer calories. In fact, it relies on the fact that you will lose weight naturally when you detoxify your body and eliminate any toxins you have in your system. Now, even if these ingredients in AdvaClear works, there is no guarantee that detoxification will actually help reduce your weight.
- Not effective for everyone
- Do not last a month
- Laxatives and caffeine
- Possible side effects
- Very expensive
It is also important to note that most experts are not in favour of detoxification because they believe that your body already has a mechanism to get rid of toxins. You can certainly try certain ingredients like selenium, watercress, artichokes, green tea extract, and more to strengthen your digestive system and liver, but there is no guarantee that taking all these supplements is going to flush toxins out of your system. Your body has to deal with those toxins in its own way, so it is better to leave it alone and let it detoxify itself naturally.
Many ingredients in AdvaClear have laxative effects, such as watercress, selenium, artichokes, milk thistle, etc., and it is possible to develop diarrhoea, which is considered a form of ‘detoxification’ by many. If it happens, you may end up losing healthy bacteria from your gut, which is going to hurt your digestion and cause all sorts of health-related problems. Once you have disturbed that balance, taking probiotic supplements may not help. Therefore, using laxatives for colon cleansing is never a suitable choice.
Some of these ingredients also work as diuretics, so you may lose water weight in the first few days that may seem like weight loss, but that is not the case actually. It can lead to several side effects as well:
A researcher at Georgetown University in Washington, DC, and his colleagues reviewed 20 studies on colon cleansing published in medical literature over the past decade. The reports showed little evidence of benefit but plenty of negative side effects, including vomiting, electrolyte imbalance and kidney failure.
What it means is that AdvaClear does not help with detoxification. There is no mention of what types of toxins the product is going to target or exactly when the detoxification process will complete. Even if it does support detoxification, there is not enough evidence suggesting that detoxification is an effective way to lose unwanted pounds. Therefore, it is better to avoid wasting money on AdvaClear and try something that targets those layers of fat effectively.
What Does AdvaClear Claim To Do?
AdvaClear by Metagenics supports detoxification. It is supposed to improve your liver health to produce some amazing results. Here are some of its claimed benefits:
- It helps improve your liver function.
- It supports overall liver health.
- It helps improve energy and vitality.
- It helps eliminate toxins to promote well-being.
- It detoxifies your body to boost metabolism.
- It helps reduce weight through detoxification.
Does AdvaClear Work?
AdvaClear makes big claims mainly because it offers a combination of vitamins, minerals, and natural ingredients. While it may support your overall health, it is not going to work great to eliminate toxins from your system to trigger weight loss. It promises to support detoxification to help lose weight, but the problem is that there is not enough scientific evidence suggesting that detoxification is going to work for weight loss. Some ingredients like watercress, artichokes, milk thistle, and even green tea may work as diuretics and eliminate water weight. This is not weight loss in the true sense. You will regain that weight as soon as you stop taking the supplement. Therefore, instead of looking for something that improves just liver health and promises to detoxify your body to trigger weight loss, you should opt for product that contains scientifically proven fat burners.
What Are The Ingredients of AdvaClear?
AdvaClear contains several ingredients. There is a mix of vitamins, minerals, and other natural ingredients. Here are some of the main ingredients found in AdvaClear:
- Milk Thistle: It is supposed to improve your liver function to promote cell regeneration. Unfortunately, there is no reliable scientific study confirming the role of milk thistle in liver detoxification.
- N-Acetyl-L-Cysteine: Your body uses it to produce glutathione that acts as an antioxidant. You do not always need it in a supplement form though.
- Selenium: It is supposed to improve your immune system and promote growth of T helper cells, but it seems that there is not enough of it in AdvaClear.
- Molybdenum: It is supposed to work by breaking down proteins and improving your overall health. Most people get enough of it from dietary sources.
There are many other vitamins, minerals, and other ingredients like artichokes, green tea extract, watercress and more, but they do not play a big role in liver detoxification or weight loss.
Does AdvaClear Have Any Side Effects?
AdvaClear is a combination of vitamins, minerals, and some natural ingredients. However, it does not mean that you do not need to worry about any side effects. There are vitamins and minerals, and taking them when you do not already have a deficiency can cause serious complications. You may develop gastrointestinal symptoms when taking these vitamins and minerals.
There is trace mineral called molybdenum that has a role to play in glutathione pathways, but it can lower copper levels in your body. If this happens, you might end up developing gout-like symptoms. This might also result in decreased blood cell production. It can even be toxin in high doses.
There is artichoke leaf extract in AdvaClear, which is supposed to improve digestion, but it can sometimes cause nausea and stomach pain as well. Similarly, watercress may be associated with an allergic reaction and produce other symptoms such as breathing problems, chest tightness, and gastrointestinal irritation. The allergic reaction could also be the result of milk thistle, which can also cause other issues, such as blood clots, constipation, bloating, eczema, diarrhoea, fever, decreased platelets, headache, giddiness, impotency, and heartburn.
Excess vitamin A intake may be toxic, may increase the risk of birth defects, and may contribute to osteoporosis. Pregnant women and women who may become pregnant should not exceed 10,000 IU of preformed vitamin A (retinyl palmitate) per day unless directed to do so by a healthcare practitioner. If pregnant or nursing, taking other nutritional supplements, or taking medications, consult your healthcare practitioner before use. To be taken under supervision of a healthcare provider. Keep out of the reach of children.
Are There Any Customer Reviews For AdvaClear?
AdvaClear makes big claims, but there are not enough positive customer reviews to support those claims. Most people are not happy with how it works.
I have been taking it for a few days but I think I’d have to stop since I am experiencing a severe abdominal pain.
I do not think it is the right way to lose weight. You will develop diarrhoea, but guys, you should never take it as weight loss.