Updated May 20, 2019.
Published May 20, 2017.

Released by Top of the World Distributors, Calotren is essentially a weight loss supplement that works by increasing your intake of collagen hydrolysate, the levels of which go down with age. Is it better than other weight-loss products that combine a number of fat burners? Can collagen hydrolysate offer any fat loss benefits? Here is our review to help you decide.


  • May help improve joint health
  • Easy to use
  • Capsules and liquid form available
  • Does not contain caffeine or stimulants


  • Very slow to produce results
  • No scientific data to prove the claims
  • Not suitable for vegetarians
  • May only work for people over 40
  • Very expensive
Calotren is one of many supplements available in the market that claim to reduce weight by boosting your metabolism. It provides you with collage protein or collagen hydrolysate to fire up your metabolic rate. At the same time, it is supposed to help you sleep better, relieve joint pain, and improve your overall health. It is available in tea, capsule, and liquid form.

Calotren Overview

What you need to know about Calotren

Calotren provides you with a simple way to increase your intake of collagen protein. You have to take four capsules a day – or you can also use it in liquid form if you do not feel like taking capsules daily. While there is some evidence that collagen helps improve the health of your bones, digestive system, and cardiovascular system, there is no data available to confirm that collagen or Calotren will help boost weight loss, especially in the absence of a well-rounded diet and exercise plan.

What are the side effects of Calotren?

The official website has not mentioned any side effects associated with the use of Calotren, but you are likely to experience stomach issues, not just because it contains collagen but also because it includes aloe Vera in the mix. Check out our ‘Side Effects’ section for more details.

How much does Calotren cost?

You can find it in both capsule and liquid form. You will be paying $69.95/bottle.

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Calotren Key Features

Calotren Weight Loss is one of many weight loss supplements currently available in the market, but unlike other supplements that use natural ingredients and fat burners, it provides you with collagen protein to help you put on some lean muscle. It relies on the fact that your body is going to burn a higher percentage of fat when you have lean muscles. While it is true that lean muscle supports your body to burn calories, there is no scientific or clinical research to confirm if Calotren or collagen protein helps build lean muscle.

Collage protein or collagen hydrolysate (CH) is supposed to offer health benefits because it is made up of amino acids. As it is an animal-based supplement, it is not suitable for vegetarians. There is no vegetarian-friendly version available, so this is another reason why many people will never feel attracted toward Calotren. CH is obtained from porcine, cow, or fish and is then processed in a way that it dissolves in cold or hot liquids with ease. It contains several amino acids, but is rich in glycine and proline. While there is limited human research confirming health benefits of collage supplements, some studies indicate that glycine and proline may be responsible for good effects.

It is important to mention that whatever scientific research done on collagen protein says nothing about its benefits on body weight. It may prove beneficial in other ways, as evident from the following studies:

A 4-week study of women aged 35–55 found that a daily intake of just ½ to 1 teaspoon of CH resulted in a significant improvement in skin elasticity. The improvements continued to remain sizeable at 8-weeks, though supplementation of CH had been discontinued.

In another 4-week study of women in their 30s, supplementation with ½ to 2 teaspoons of CH resulted in a substantial improvement in the moisture content of facial skin.

However, a few studies have shown that collagen protein contains such amino acids that may ‘indirectly’ help overweight people. For instance:

In a 2008 issue of The European Journal of Pharmacology, glycine is said to possess powerful anti-inflammatory properties, and has the ability to increase the protein adiponectin. Also considered a hormone, adiponectin is a key player in regulating glucose levels, and making sure those fatty acids get broken down. This can be particularly useful in cases of obesity and diabetes Type 2.

Even if that is how collage hydrolysate works, you will have to wait for several months before noticing any change in your weight. It is also important to point out that some studies show positive effects of hydrolysed collagen products, but they are actually sponsored by the manufacturer itself.

Calotren Key Points

  • 120 capsules per bottle
  • 32 servings in liquid form
  • Easy to take

Another noticeable thing is that makers of collagen products usually do not encourage exercise. This is another loophole in the whole plan. Some studies show that collagen protein may strengthen connective tissue in your body, but there is no evidence at all that collagen or Calotren can promote muscle building. You will have to exercise to put on lean muscle and then supplement with Calotren to get better results.

Calotren is less likely to work also because it says nothing about how much of collagen protein there is per serving. A reputable supplement that actually has scientifically proven ingredients actually feel proud to share their formula along with how much of each ingredient is there in the blend. Using a proprietary blend is never a good strategy. Moreover, the manufacturer says nothing about what type of collagen is in the mix. Chicken collagen is considered more beneficial for joint health, whereas fish collagen is considered more effective for the health of your skin, digestive system, bones, and blood vessels. Bovine collagen is supposed to have a higher supply of proline and glycine, so it may be more helpful in muscle building, but it may be associated with Mad Cow Disease and other livestock illnesses.

Also, keep in mind that you should not take Calotren as a dietary supplement because it only contains 8 essential amino acids. CH has very little of isoleucine, methionine, and threonine, whereas it does not contain tryptophan. You will have to deal with complications if you do not take Calotren with a well-balanced diet.

There is no scientific evidence to support the efficacy of the formula used in Calotren – they have not shared any clinical data in this regard. They say you should take four capsules of Calotren before going to bed – it should be 3 hours after dinner. You have to take it with water and not eat anything after that. There is no research or scientific evidence to support that taking collagen protein at bedtime is going to boost your metabolism or facilitate the process of fat loss.

How to Take Calotren

You have to take 4 capsules at bedtime. Be sure to take it on an empty stomach with 8 oz of water. You should not eat anything after you have taken it. You can also take it in liquid form – you have to take 1 tablespoon or 15 ml of liquid Calotren daily.

An interesting thing to consider is that Calotren relies on the fact that your collagen levels decline as you age and it provides you with collage protein to improve those levels and support lean muscles. Even if we suppose that Calotren is effective, it is not going to work for people under 40 years of age if they are not already deficient in collagen. There is no fat burner included in the formula, which is the reason why you are not going to get any results if you do not really need collagen in the first place. If you are young and obese, Calotren is certainly not for you.

Calotren Concerns

  • No scientific evidence to support its use
  • Proprietary blend
  • No money-back guarantee for unsealed items
  • Very expensive

It is never a good idea to spend $69.95 on a supplement that may or may not work for you. Interestingly, it will be a little inexpensive to buy it in liquid form. You will be paying the same amount of money ($69.95) for both, but there are 120 capsules per bottle, which means you get a 30-day supply. If you opt for the liquid form, you actually get 32 servings per bottle. Of course, the difference is not huge, and many people are still going to find it a very expensive way to supplement their weight loss efforts, especially when their money-back guarantee is not that impressive. They have a 45-day money-back guarantee, but also state that you are not going to see any results when you use Calotren for less than 45 days.

The fact of the matter is that while Calotren makes big claims, you should not expect much in terms of fat loss. If you really want to slim down or shed some additional pounds, pay attention to your diet and opt for a weight-loss supplement that is backed by supportive customer reviews and real scientific studies.

What does Calotren claim to do?

Calotren Weight Loss makes big claims, and they actually sound quite unrealistic considering there is no real scientific data to confirm the benefits of collagen protein for fat loss. Here is what the company has stated on their official website:

Calotren Advanced is a natural weight loss formula created to help your body burn fats and sugars more efficiently. This effective supplement combines Collagen Protein with our?exclusive digestive enzyme formula to maximise your benefits. By pre-digesting the protein, Calotren Advanced?helps your body absorbs the protein up to 3 times faster, break it down easier and achieve the goals you’ve always wanted!

Does Calotren work?

Unfortunately, it does not. The main idea behind using Calotren for weight loss is to increase your intake of collagen hydrolysate, which in turn will change how your body stores and uses fat. There is no clinical data to prove that collagen protein helps you achieve your weight loss goals. It may be beneficial for your bones, joints, and even cardiovascular system, but there is not enough scientific evidence to support its use for obesity. Even if it works, it will take long before you see any change in your weight. It is better to use a supplement with fat burners, such as green tea extract, yohimbe, chromium, ALA, etc., to boost metabolism and suppress appetite. And of course, follow an exercise program to lose weight efficiently.

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Calotren Ingredients

Calotren Weight Loss provides you with collagen hydrolysate to help you lose weight. Although there are other ingredients as well, it relies mainly on CH to produce results.

Collagen Hydrolysate (CH) is gaining popularity because of its better bioavailability. It means your body can digest it easily. You are likely to see benefits because it contains amino acids that are used by your body to improve vascular system, skin, muscular system, smooth muscle tissues, and skeletal system. Unfortunately, there are not enough human studies to confirm that CH has any medicinal use.

Other ingredients: water, collagen hydrolysate, aloe vera, vegetable glycerine, natural and artificial flavour, potassium sorbate, citric acid and sodium benzoate.

Calotren Side Effects

No information about side effects is available on the main website. However, some customer reviews suggest that Calotren is not a safe option for everyone. Some customers complain about experiencing constipation, while others have to deal with diarrhoea. These gastrointestinal problems are mainly due to aloe vera.

Due to the ingredients, you also are at an increased risk of dealing with allergic skin reactions, dehydration, and constipation. It sometimes leads to an imbalance in electrolytes and causes heart rate problems and slow healing.

You may want to avoid using the Calotren if you are not already deficient in collagen because an overdose can cause certain problems, such as bone pain, fatigue, and abnormal heart rhythm.

Caution: Not suitable for individuals under 18. Avoid if you are pregnant or breast-feeding. Consult your doctor before taking any supplements, especially if you are taking any prescription medications.

Calotren Customer Feedback

Customer reviews do not tell great stories about Calotren either. Here are a few examples:

If you are at all sensitive to taking pills, don’t do this! I followed the instructions, waited the 3 hours after eating before taking it, and then barely slept all night. It says “no stimulants” but something kept me awake and feeling sick all night.

Well, it doesn’t work for my wife, and she not very happy about this product I think she gain weight instead of losing.

I tried Calotren for a month and received no results. I worked out, cut back food intake and didn’t eat after 7 pm every night. I didn’t feel any different health-wise either. I would not recommend this product.

Calotren Money-Back Guarantee

Yes, it comes with a 45-day money-back guarantee, but you will not be able to get a refund for a product that you have opened already.

Where To Buy Calotren

You can buy it directly from the official website.

Watchdog Verdict

There are some good things about Calotren, like it is easy-to-take and contains no stimulants. But that does not mean it deserves your attention mainly because there is not enough scientific research to support the benefits of taking collagen hydrolysate. The company uses a proprietary blend, so we do not know how much of collagen protein is there in mix. Moreover, the company mentions that you should pay attention to your overall diet and follow an exercise program but it does not offer any guidance in this regard. What it implies is that you are less likely to see any results if you take Calotren but do not start eating clean. It is not an affordable supplement either. So, look for a supplement with scientifically proven fat burners to get better results.

How does Calotren compare to Phentaslim?

Criteria Calotren Comparison Phentaslim comparison
Clinically Proven Ingredients
Side Effect Free
Positive Customer Reviews
24/7 Support
Money-back Guarantee

Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

Have Your Say

1 comment on 'Calotren'

  1. My fiance has raynauds disease, (poor circulation), took calotren and had a stroke. Several doctors and a neurologist said that it was caused from taking this diet pill.

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