Dexaprine XR

Updated May 17, 2019.
Published Feb 22, 2016.

The most important thing to mention about Dexaprine XR is that it has been banned in several countries (including the UK). The reason for this is that it contains potentially dangerous ingredients. An older version of this product, just called Dexaprine, used to contain DMAA, but this was removed and the updated version had XR added to the name. Even still, this product counts bitter orange extract as an ingredient, as well as some synthetic, amphetamine-like ingredients that are not listed on the label, but were found in the formula by a group of Dutch researchers.


  • None


  • No money-back guarantee
  • Banned in the UK and The Netherlands
  • Huge list of side effects
Dexaprine XR
Dexaprine and Dexaprine XR are two diet pills that have been banned in both the Netherlands and the UK in 2014 following concerns about the side effects caused by the product. Whilst it is now almost impossible to purchase Dexaprine, Dexaprine XR is still widely available to US consumers.

Below, we take an in-depth look to see how effective Dexaprine XR is as a weight loss aid, as well as how safe the supplement really is.

Dexaprine XR Overview

What you need to know about Dexaprine XR

The customer reviews and ingredients list both suggest that this product could significantly increase the body’s metabolic rate, as well as increase energy levels. It is thought by some that one ingredient, Acacia Rigidula, contains compounds that could suppress the appetite significantly, but there is almost no detailed research into Acacia Rigidula and its effects upon the body.

The main problem we have with this product is its strength; the product is so strong that even the most experienced of stimulant supplement users, including bodybuilders, report a variety of side effects associated with this product. The huge variety of serious side effects and their severity has even led to the product being banned in the UK and the Netherlands. Dexaprine XR may theoretically work to aid weight loss, but it can also lead to horrible and unpleasant side effects that could even result in a trip to the hospital.

What are the side effects of Dexaprine XR?

Dexaprine XR has such dangerous potential side effects that it has been banned in several countries. For a full list, please see the Side Effects section below.

How much does Dexaprine XR cost?

As it has been banned, you cannot buy Dexaprine XR from the official website any more. Some third party retailers still sell it, but prices will vary.

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Dexaprine XR Key Features

Dexaprine XR is a thermogenic diet pill manufactured by iForce Nutrition, a company based in California, USA. They offer a range of weight loss and workout or training related supplements, including TT-33 which we have previously reviewed here.

Dexaprine XR Key Points

  • Manufactured by iForce Nutrition.
  • 60 capsules per bottle.
  • Ingredients list may not match actual ingredients.

iForce Nutrition describe themselves as marking ‘the beginning of interactive nutritional science’, and as the:

first human performance company to bridge the gap between the functionality of innovative cutting-edge nutritional science and the interactive application of nutrition for athletic performance enhancement. A revolutionary new approach that guarantees the results you demand.

They can be contacted using the information provided on their official website.

How to Take Dexaprine XR

As a dietary supplement, take 1 caplet on an empty stomach before breakfast. If you want extreme results, take 1 caplet on an empty stomach before breakfast and then another caplet 6-8 hours later. Do not exceed two caplets per day.

The UK Medicines and Healthcare products Regulatory Agency (MHRA) considers “Dexaprine XR an unlicensed medicinal product”, and as such banned the sale of Dexaprine XR within the UK in August 2013. Dexaprine XR is also banned in the Netherlands.

Dexaprine XR Concerns:

  • No money-back guarantee.
  • Banned in UK and The Netherlands.
  • Huge list of side effects.

The original formula of Dexaprine contained DMAA, but Dexaprine XR and other current formulations of Dexaprine apparently do not contain DMAA. However, USA Today reported in May 2014 that Dutch researchers found a ‘cocktail of synthetic stimulants’ in Dexaprine, including ‘a synthetic amphetamine-like compound and deterenol, a compound briefly explored in pre-clinical drug development but never fully researched for its effects in humans.’ iForce Nutrition, the manufacturers of this product, have been in trouble before, pleading guilty to manufacturing supplements containing synthetic steroids back in 2011.

What does Dexaprine XR claim to do?

According to one sales website, the benefits of Dexaprine XR are as follows:

  • 7-8 hours of energy from 1 pill
  • Blast hunger pains and reduce cravings
  • Take 1 pill per day and the bottle lasts 2 months
  • Can be taken by men and women
  • Burns fat

Does Dexaprine XR work?

Caffeine is known to boost the metabolism for a few hours after consumption, and may have a very mild effect upon the appetite, although this is short lived. The product contains both caffeine as a separate ingredient, and green tea, which naturally contains some caffeine. Green tea also contains a variety of catechins. Some of these, especially EGCG have been linked with increased thermogenesis in the body. Thermogenesis is the creation of heat which burns calories in the process, and so could contribute to weight loss efforts.

Bitter orange extract is a stimulant ingredient that will increase the metabolism. When combined with caffeine, as it is in this supplement, the effects of both are amplified.

Acacia Rigidula is under-researched, especially considering that it naturally contains so many different compounds that could have a whole range of effects, both positive and negative, on the body.

One concern we have with this product is that a group of Dutch researchers found ingredients in Dexaprine XR that were not listed on the label; whilst it is possible that some of these compounds are found naturally in Acacia Rigidula, which contains over 40 different compounds, there were some ingredients that were synthetic and amphetamine-like in their structure.

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Dexaprine XR Ingredients

The ingredients used in Dexaprine XR, according to one sales website, are listed below. The individual ingredient quantities are not provided, as the product consists of three proprietary formulas. There is a total of 645 mg of the active ingredients per capsule, according to the label.

Dexaprine Tri-Phase Ignition System 645 mg

Thermophoric Amine Mood Enhancement Complex:

  • Acacia Rigidula Extract (98%): This plant, originating in Texas, Mexico and Africa, supposedly contains over 40 active compounds, some of which are thought to increase the metabolism, as well as lipolysis in the body. However, very little investigation has been made into this plant in relation to weight loss, and so our knowledge of the plant is based on speculation rather than clinical results.
  • Citrus Aurantium (30% active amines): Citrus Aurantium, also known as bitter orange peel, has been proven to raise the metabolism and aid weight loss. It contains a number of different compounds that have been associated with weight loss, including synephrine. A review of numerous studies concluded that use of synephrine resulted in an increase to the participants resting metabolic rate and energy expenditure, and moderate weight loss was seen in studies lasting over 6 weeks. However there are some concerns about its safety.

Extended Release Energy Complex:

  • Caffeine Anhydrous: Numerous studies have shown that caffeine boosts energy levels and alertness, as well as mildly boosting the metabolism. The effects shown in studies are small, and some studies are inconclusive.
  • Green Tea Extract (Standardized for Theophylline): Green tea is high in a group of antioxidants called catechins. Studies have suggested that catechins increase thermogenesis in the body, whilst caffeine increases energy expenditure by boosting the metabolism slightly for few hours. Theophylline is used to treat wheezing and other breathing difficulties.

Alpha-2 Adrenergic Activation Complex:

  • Rauwolfia Serpentina (Standardized for Rauwolscine): Lowers blood pressure. It could counteract the increase in blood pressure caused by caffeine and citrus aurantium.
  • Isopropyloctopamine: a chemically modified version of Octopamine.

Dexaprine XR Side Effects

There are numerous ingredients used in Dexaprine XR that could cause a range of different side effects, some of which could be very serious. The product has been banned in two countries already because of numerous reports of side effects, including ‘nausea, agitation, palpitations and one cardiac arrest’.

Side effects associated with the use of Bitter Orange include increased heart rate and increased blood pressure, heart palpitations, fainting, and even heart attack and stroke in healthy patients. The Mayo Clinic has recommended avoiding use of Bitter Orange and its extracts because in their opinion, the risk of using the product is not worth the pay-off of some weight loss that could be achieved using other means. Consumers should remember that the effects of the stimulants found in Bitter Orange are enhanced when combined with caffeine.

Significant quantities of caffeine can cause side effects such as headaches, increased urination, dehydration, jitteriness, increased heart rate, increased blood pressure, heart palpitations and problems sleeping. Green tea and guarana are also sources of caffeine. Green tea can also cause constipation.

Rauwolfia Serpentina can cause dryness of the mouth, drowsiness, depression, vivid dreams or nightmares. It will also lower blood pressure. It should not be combined with antihistamines or alcohol, as it can add to their effects and cause drowsiness.

Acacia Rigidula contains nicotine, and so could be addictive. It has also been associated with numerous other side effects, including increased blood pressure, increased heart rate, jitters, stomach ache, energy crashes after a few hours, and light-headedness. There could be many more side effects of this ingredient, as it has been severely under-researched, and has never been researched in humans over long-term use.


Not to be used by those under the age of 18. Not suitable for pregnant or breastfeeding women. Not suitable for those who have any serious medical condition or are taking any prescription or over the counter medication. Not suitable for anyone who is sensitive to caffeine and other stimulant ingredients. Not suitable for anyone with high blood pressure, or any other cardiac-related health issues. Consult your doctor if you are unsure about the suitability of this product for you. Stop using at least two weeks before any surgery.

Dexaprine XR Customer Feedback

There are numerous customer reviews for this product. Many of the positive reviews compare it favourably with other diet pills that are no longer available, as they were pulled from the market due to their ephedra content (a now-banned stimulant that causes a huge range of serious side effects).

I couldn’t imagine taking it every day for a week. My heart pounded so strong it was uncomfortable to the point of being very unpleasant. And I’m no stranger to pre work out performance sports enhancement supplements.
Sits on my shelf…..sorry I bought it but the copy was compelling and I’m trying to get rid of love handles that exercise alone isn’t helping.

This Dexaprine works. I’ve used 4 bottles over the last two years at different body stages over that time. It works every time. I have to set my alarm and remind myself to eat otherwise, i’d go all day without eating. Lots of energy. It can make you a bit jittery at times.

Dexaprine is definitely a go to supplement for me! It suppresses my appetite perfectly and definitely helps to drop some weight when I need it!

If you want a big jolt of caffeine jitters, you’ll get it with this if you take the whole tab. I started with half a tab, as recommended, but didn’t really notice anything, just a mild caffeine buzz. So the next time I took a whole one, and about an hour later my heart started pounding extremely hard and my hands were shaking. That lasted about 2 hours. As discomfiting as that was, it would be worth it if they worked as an appetite suppressant, but they absolutely did not, just made me hungrier.

Best thing since the original OxyElite Pro formula! Haven’t yet tried anything that works as well as this. I can only take half a dose, as it makes me incredibly jittery for hours! But curbs appetite, gives lots of focus and energy, and is the only thing since OxyElite that I have found works!

Makes me extremely irritable where I was snapping on my family for anything. Sounds light everything was very irritating. Didn’t notice any energy from the product did suppress appetite a little bit but there’s far better products out there.

Overall a solid and very strong fat burner. Consistent energy that lasts throughout most of the day.
If you are sensitive to fat burners or similar products then I recommend you look for another product. If you are looking for a strong product that is consistent then I would highly recommend.

Dexaprine XR Money-Back Guarantee

There is no money-back guarantee for this product. Returns policies will vary by individual retailers.

Refunds are typically not given if the customer does not receive the product because of their nation’s import and customs regulations.

Where To Buy Dexaprine XR

Dexaprine XR is not available direct from the manufacturers. As it is no longer legal to sell this product in the UK, there are many third party retailers that have sales pages for the product, but have added that the product is permanently discontinued. This includes eVitamins’ UK store and All Star Health.

A single bottle of Dexaprine XR costs $28.99 plus delivery charges when purchased from Best Price Nutrition. The company also offer multi-buy discounts: ‘Buy 2 for $27.99 each and save 4%’ or ‘Buy 3 for $26.99 each and save 7%’.

Dexaprine XR is also available from Supplement Warehouse, for $19.99 per bottle plus delivery costs. Each bottle contains 60 capsules.

Because the product is banned in both the UK and the Netherlands, anyone who is ordering the product in these countries from abroad could have the product confiscated and destroyed at customs. Refunds are typically not given if the customer does not receive the product because of their nation’s import and customs regulations.

Watchdog Verdict

Overall, we are not impressed by Dexaprine XR at all, and advise all of our readers to avoid the product, no matter how ‘stim-tolerant’ they proclaim themselves to be. The product is not safe, with a huge list of severe side effects being reported and two countries banning the sale of Dexaprine XR due to health and safety concerns.

The product has been investigated by Dutch researchers, and they found that Dexaprine XR contained ingredients that were not mentioned on the ingredients list, one of which is synthetic and appears to be similar to amphetamines.

The product is not covered by any money-back guarantee, and some of the companies that still sell the product have dodgy reputations online, with one site even claiming that they have the original Dexaprine (complete with DMAA) in stock. Because of the DMAA content original formula Dexaprine is banned in numerous countries as well, and is no longer in production.

British and Dutch customers who do order the product risk it being confiscated at customs.

Overall, we do not recommend Dexaprine XR to our readers. It is an unsafe option that could potentially cause long term health problems, and so we advise our readers to avoid it at all costs.

How does Dexaprine XR compare to Phentaslim?

Criteria Dexaprine XR Comparison Phentaslim comparison
Clinically Proven Ingredients
Side Effect Free
Positive Customer Reviews
24/7 Support
Money-back Guarantee

Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

Have Your Say

1 comment on 'Dexaprine XR'

  1. I had to break them all in half…. I almost passed out at the gym it was bad… I DO NOT recommend this product. This product needs to be banned. It will make you extremely jittery. Your heart beat unbelievably fast. Beware

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