• EvoMuse Defuse

    Whilst some weight loss supplements are designed to help maximise your weight loss whilst dieting, others are designed to help counteract fat gain during “bulking” phases, where bodybuilders are trying to gain as much muscle as possible.

    Below we take an in-depth look at EvoMuse Defuse to see how effective this supplement is at preventing fat gain.

    EvoMuse Defuse Pros

    • Some clinical support (but studies used mice, not humans)

    EvoMuse Defuse Cons

    • No money back guarantee
    • No customer reviews
    • Limited availability
    Watchdog Rejected

    EvoMuse Defuse

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    What You Need To Know About EvoMuse Defuse

    EvoMuse Defuse is a weight loss supplement designed to help to “prevent fat gain by preventing the mechanisms for fat storage from working optimally, leaving the body with no choice but to burn that fat away”. It also features some fat burning ingredients, such as the stimulant Citrus Aurantium. The majority of the active ingredients only have support from a single study in mice each, making this a very experimental blend.

    What Are The Side Effects Of EvoMuse Defuse?

    With such a long ingredients list, there are numerous side effects that could develop whilst taking EvoMuse Defuse.

    Many of the ingredients used in this supplement have not been studied extensively in humans, and so the potential side effects of these ingredients are largely unknown. There is also little information available about the ideal dosing of these ingredients.

    Side effects associated with the use of Citrus Aurantium and its extracts such as synephrine, include increased heart rate and increased blood pressure, heart palpitations, fainting, and even heart attack and stroke in healthy patients. The Mayo Clinic has recommended avoiding use of Bitter Orange extract because in their opinion, the risk of using the product is not worth the pay-off of any potential weight loss. The effects of synephrine and other bitter orange extracts are enhanced when combined with caffeine.

    Olive leaf can lower blood pressure. People who already have low blood pressure could experience side effects such as dizziness, lightheadedness, and even fainting. Other side effects of Olive Leaf include stomach irritation, diarrhoea, and heartburn.

    How Much Does EvoMuse Defuse Cost?

    EvoMuse Defuse can be purchased from the Evolutionary Muse website. Here a single bottle costs $44.99, plus delivery charges.

    From Predator Nutrition, a bottle costs £34.98, plus delivery charges. This appears to be the old formula, but this may be updated to the new version at any time.

    Our Verdict On EvoMuse Defuse

    EvoMuse Defuse appears to have a significant amount of clinical evidence supporting the idea that it could inhibit fat gain, but the majority of this evidence comes from preliminary studies in mice, and many of the active ingredients have not been studied in humans for weight loss purposes. Because of the lack of studies in humans, the potential side effects of these ingredients are largely unknown. There is also little information available about the ideal dosing of these ingredients.

    In general, this means that EvoMuse Defuse contains a very experimental blend. Many of the ingredients are not commonly found in supplements. We want to see more studies in humans before we can endorse the supplementation of any of the ingredients that have only been tested in mice. The product also uses citrus aurantium, a stimulant that can cause a range of unpleasant side effects.

    EvoMuse Defuse is not covered by a money back guarantee. Because the supplement was reformulated just a few months before this review was written, customer reviews are lacking in general.

    Overall, we do not recommend EvoMuse Defuse to our readers.

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    EvoMuse Defuse Review

    EvoMuse Defuse is a weight loss supplement designed to help to “prevent fat gain by preventing the mechanisms for fat storage from working optimally, leaving the body with no choice but to burn that fat away”. It also features some fat burning ingredients, such as the stimulant Citrus Aurantium.

    EvoMuse Defuse Facts

    • Manufactured by EvoMuse (Evolutionary Muse)
    • 240 capsules per bottle

    It appears that EvoMuse Defuse was reformulated at some point before November 2017. It also appears to have a limited availability in winter. The manufacturers posted the following to their Facebook account: “Apparently running defuse in the Winter is going to be the last time due to the humidity and potency of the extracts. That means this is going to be it until April.”

    How to Take EvoMuse Defuse

    Directions for use are as follows: As a dietary supplement, take 3 capsules 30 minutes prior to the largest meals of the day.

    EvoMuse Defuse is manufactured by EvoMuse, also known as Evolutionary Muse, who are based in the USA. They do not provide their full address on the website, and customers who want to refund a product should email them through orders@evolutionarymuse.com in order to initiate the returns process and be given a postal address. EvoMuse appear to be very active on their Facebook page, making it a great place to contact them.

    EvoMuse Defuse Concerns:

    • No money back guarantee
    • No customer reviews
    • Limited availability

    What Does EvoMuse Defuse Claim To Do?

    The manufacturers make the following claims about EvoMuse Defuse.

    “The Defuse formula helps to prevent fat gain by preventing the mechanisms for fat storage from working optimally, leaving the body with no choice but to burn that fat away.”

    “Prevents fat gain when bulking
    Can be used before big meals to prevent fat gain
    Long term use of Defuse enables improved repartitioning
    Ideal before a cheat meal
    When dieting, Defuse can help you mobilise fat more readily”

    Does EvoMuse Defuse Work?

    The majority of the ingredients found in EvoMuse Defuse are supported by clinical trials in mice but have not been studied in humans for weight loss purposes. This makes EvoMuse Defuse a very experimental formula that could theoretically work, but on the other hand it could have no beneficial effects at all.

    More studies, preferably in humans, are needed to see whether the ingredients found in EvoMuse Defuse can inhibit fat gain, as claimed by the manufacturers.

    What Are The Ingredients of EvoMuse Defuse?

    The ingredients found in the new formula of EvoMuse Defuse are detailed below. The ingredient quantities listed are per serving of four capsules.

    • Acacia Catechu 20:1 200 mg: Acacia Catechu is a plant thought to treat obesity, and has been used in Ayuvedic medicine for thousands of years. However, there is no clear clinical support for its use as a weight loss treatment. Source
    • Platycodon Grandiflorum 20:1 250 mg: also known as the balloon flower. It has been used in Chinese medicine traditionally, and some studies suggest that the saponin content could have numerous health benefits. May improve insulin resistance. A single study in mice found that it suppressed weight gain when the mice were supplemented the active ingredient and fed a high fat, high calorie diet. It has not been tested in humans for weight loss purposes. Source
    • Baicalin 75 mg: Baicalin, the active compound from the Blue Skullcap, appears to have numerous health benefits, but many studies were in animals or test tube studies. One animal study found that after 16 weeks of Baicalin use, animals on a high-fat diet had a lower weight and less fat accumulated in their livers than those not on Baicalin. Again, this has not been tested in humans, but theoretically Baicalin could help to prevent fat gain. Source
    • Rose Ellagitannins 150 mg: One study in mice suggests that Rose Ellagitannins could help to treat some metabolic disorders, and could aid weight loss. Again, this has not been tested in humans, and has not been replicated in other studies yet. Source
    • 18b-Glycyrrhetinic Acid 50 mg: Masks bitter flavours.
    • Cinchona Bark Alcohol Extract 20:1 75 mg: A medicinal herb which contains a variety of alkaloids which are used for different treatments. This included quinine, used to treat malaria. It is also traditionally used to stimulate appetite, but some animal studies also suggest that it could help to limit weight gain, without affecting food intake. Source

    (-) Hydroxycitric Acid 125 mg

    • Taxillus Tieghem 20:1 100 mg: Taxillus Tieghem has induced weight loss in mice in one study, and significantly reduced their food intake as well. Source
    • Citrus Aurantium 100 mg: Also known as Bitter Orange Peel, this ingredient contains synephrine. A review of numerous studies concluded that use of synephrine resulted in an increase to the participants resting metabolic rate and energy expenditure, and moderate weight loss was seen in studies lasting over 6 weeks. However, there are some concerns about its safety being under-researched and the numerous side effects that have been associated with it. Source
    • Lotus Leaf 20:1 150 mg: Used to treat stomach problems including diarrhoea. There is little clinical evidence to support the effectiveness of this ingredient. Lotus leaf has been used to treat obesity, but there are no studies available in humans. Source
    • Olive Leaf 20:1 200 mg: May lower blood pressure and cholesterol levels. Source
    • Galega Officinalis 20:1 250 mg: Also known as Goat’s Rue. Acts as a diuretic, and could potentially lower blood sugar levels (although this has not been tested in humans). Source
    • Fermented Panax Ginseng Berry 20:1 175 mg: Panax Ginseng, also known as Korean Ginseng, is associated with improved cognition in fatigued subjects and slight decreases in muscle damage after exercise. It also appears to reduce fatigue, and consumers report feeling calmer after consumption. Source
    • Forskolin 60% 20 mg: Forskolin is the active extract taken from Coleus Forskohlii, a plant related to the mint family. In one study that was looking at its potential link with weight loss, participants taking Coleus reported less fatigue. In general, Coleus is thought to boost the metabolism. However, the clinical trials performed using this ingredient have shown no weight loss, even when the participants’ lean muscle mass increased and fat mass decreased. Source
    • Methyl Cinnamate 75 mg: Used as a flavouring and to provide fragrance, as it smells like cinnamon and strawberry. We were unable to find any active benefits of this plant extract. Source
    • Silibinin 60 mg: Extracted from milk thistle seeds. One study shows that it causes weight loss in mice. It has not been tested in humans for weight loss. Source
    • Raspberry Ketones 250 mg: Although it can be extracted from raspberries, as the name suggests, the majority of raspberry ketones used in supplements is lab-synthesised, as this is a more cost effective option. Whilst there is a small amount of evidence that raspberry ketone can cause weight loss in rats, there have never been any human trials on the potential weight loss effects of raspberry ketone. Source

    Does EvoMuse Defuse Have Any Side Effects?

    There is an incredibly long list of ingredients used in EvoMuse Defuse that could cause a range of side effects.

    Many of the ingredients used in this supplement have not been studied extensively in humans, and so the potential side effects of these ingredients are largely unknown. There is also little information available about the ideal dosing of these ingredients.

    Side effects associated with the use of Citrus Aurantium and its extracts such as synephrine, include increased heart rate and increased blood pressure, heart palpitations, fainting, and even heart attack and stroke in healthy patients. The Mayo Clinic has recommended avoiding use of Bitter Orange extract because in their opinion, the risk of using the product is not worth the pay-off of any potential weight loss. The effects of synephrine and other bitter orange extracts are enhanced when combined with caffeine.

    Olive leaf can lower blood pressure. People who already have low blood pressure could experience side effects such as dizziness, lightheadedness, and even fainting. Other side effects of Olive Leaf include stomach irritation, diarrhoea, and heartburn.

    Caution:
    Not suitable for pregnant or breastfeeding women. Not suitable for anyone under the age of 18. Not suitable for anyone who has any heart related health issues, including but not limited to high blood pressure. Not suitable for anyone who is sensitive to caffeine and other stimulants, as this product contains citrus aurantium, a strong stimulant. If you are taking any medication or have been diagnosed with any medical condition, consult your doctor before taking this supplement.

    Are There Any Customer Reviews For EvoMuse Defuse?

    It appears that EvoMuse Defuse was reformulated at some point before November 2017. This may explain the limited number of customer reviews of the product, as people simply haven’t had the time to test the new formula and leave a review yet.

    There are some older customer reviews, but these obviously refer to the old formula.

    Does EvoMuse Defuse Offer a Money-Back Guarantee?

    The manufacturers of EvoMuse Defuse do not offer a money back guarantee, and they do not accept refunds on opened products.

    They describe their returns policy as follows:

    “Product can be sent back for a full refund in the case of manufacturer’s defect only.

    Unwanted products can only be returned if they have been NOT been opened. To return an unwanted, unopened product you will be responsible for the shipping charges to ship your product back to our warehouse. To initiate the return process please email orders@evolutionarymuse.com.

    Be sure to include the following in your inquiry:

    • Order number
    • Email address used to order
    • A phone number where you can be reached
    • Why you want to return the product
    • Product description”

    Where Can I Buy EvoMuse Defuse?

    EvoMuse Defuse can be purchased from the Evolutionary Muse website. Here a single bottle costs $44.99, plus delivery charges.

    From Predator Nutrition, a bottle costs £34.98, plus delivery charges. This appears to be the old formula, but this may be updated to the new version at any time.

    How does EvoMuse Defuse compare to Phentaslim?

    CriteriaEvoMuse Defuse ComparisonPhentaslim comparison
    Clinically Proven Ingredients
    Side Effect Free
    Positive Customer Reviews
    24/7 Support
    Money-back Guarantee
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    Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.



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