iSDG Enzyme Pills

Updated May 22, 2019.
Published Nov 5, 2017.

iSDG is a Japanese company with a range of digestive enzyme supplements, currently on sale in Japan. iSDG is a shortened version of the word “Ishokodogan” which means “food and medicine from the same source”, and originates from Okinawa. According to dietary experts, the Okinawan diet is one of the best in the world when it comes to health and longevity. This doesn’t translate across to iSDG Enzyme Pills though. There are no reputable or official retailers (they just show up on eBay and Amazon, where anybody can list a product), and as such, there is very little information about what the product contains.


  • Contains fruit and vegetable enzymes


  • Inadequate ingredients information
  • No background regarding manufacture and safety standards
  • Highly unlikely to work in the way as advertised
iSDG Enzyme Pills
Digestive enzyme supplements seem to offer a safe way to improve health, weight loss, and even help protect against the aging process. iSDG Enzyme Pills is a four supplements brand that seems to be becoming increasingly popular in the UK and USA, as well as being on sale across South Asian countries.

Following a request from one of our Watchdog readers, we take a look at iSDG Enzymes to find out more.

iSDG Enzyme Pills Overview

What you need to know about iSDG Enzyme Pills

iSDG Enzyme Pills are made in Japan, according to the advertising, but in truth there is very little information about the supplements, the manufacture, the ingredients, or any other basic information you need when buying a supplement. We would be very wary about taking any of the four different products, and we cannot see any of them working in the way as described. Although achieving the longevity and health of the people of Okinawa sounds appealing, we cannot see this supplement delivering “Ishokodogan” in the same way as a healthy diet and lifestyle.

What are the side effects of iSDG Enzyme Pills?

We can’t say for sure, just what effects these pills will have. However potential side effects may include diarrhoea, abdominal discomfort, headaches, and allergic reactions.

How much does iSDG Enzyme Pills cost?

Prices vary depending on where you buy, and some sellers charge different prices for each flavour. Each bottle contains 120 capsules which should be a month’s supply.

If you buy via Amazon UK, you can find iSDG Night for £19.98. and Beauty for £18.63. The prices on Amazon USA customers are around $23.60 per supplement. You can also find iSDG supplements on sale via eBay and other websites.

If you are based in Asia the easiest way to buy is via Lazada. We found iSDG supplements on sale via the Singapore site, for between 30.90 SGD and 40.90 SGD.

WATCHDOG TIP: Consider using the consumer #1 rated weight loss product – CLICK HERE

iSDG Enzyme Pills Key Features

ISDG Enzymes are available in pill form or as a drink, and the range comprises of four different supplements which all claim unique benefits. For the purposes of this review we are focusing on the pills.

The four supplements are as follows;

  • Diet Enzyme Premium aimed at supporting weight loss. This is sometimes called Original Premium.
  • Exhilarating Enzyme for increasing energy levels and a zest for life. Sometimes referred to as Soukai Enzyme Supplement Premium.
  • Miki Enzyme Beauty for improving skin and helping age related damage
  • Night Time Diet Enzyme aimed at people who want to lose weight, but don’t seem to get around to it. According to the product information, this particular formula helps harness growth hormone as you sleep.

It is important to point out here that these supplements come with varying product information and names. This is because all the information is written in Japanese so you only have the various translations to go on, and without an official iSDG website there is no definitive information source.

iSDG Enzyme Pills Key Points

  • Each pill variety contains 232 enzyme ingredients
  • Each bottle contains 120 pills (1 month’s supply)
  • Available on Amazon, eBay, and Lazada

The supplements themselves are based on enzymes. Enzymes are forms of protein and play a role in all bodily and chemical reactions. The word “enzyme” sounds scientific, but of course the truth is that enzymes are everywhere. They are in our body where they undertake vital functions, such as helping us digestive and absorb food. Enzymes are present in all living forms across the planet, so are in the food that we eat and they are crucial to health, wellbeing, and our very existence.

All the supplements are crammed with fruit extracts and vegetables, designed to boost amino acids and enzymes in your body.

The four supplements each have a specific purpose such as weight loss or energy enhancement, but the basic ingredients list is identical for all four supplements. A few additional ingredients make the difference between each supplement.

So for example, according to the product information, the Diet Enzyme Premium supplement contains yeast, Coleus Forskoholii, and malted rice, that according to the product information will assist in your calorie burning, whereas the Night Diet Enzyme supplement contains metabolic enzymes and amino acids. Check out the ingredients tab to find out more.

How to Take iSDG Enzyme Pills

  • Take 2 tabs twice a day
  • Best taken before meals for best results

ISDG is a Japanese brand, but we don’t have much background information about the company. There is no official website or any contact details, and this company obviously do not sell direct to customers.

We have found iSDG enzyme pills on sale from various third party sellers such as Amazon and eBay, but they do not seem to be available from the more established online supplement stores. In Asia, iSDG supplements are on sale via Lazada from various third party sellers, but the overall impression of iSDG is that this company is not particularly well known or reputable.

iSDG Enzyme Pills Concerns:

  • No background information about iSDG? How can we know these supplements have been manufactured in accordance with health and safety standards?
  • Inadequate ingredients information. Effects could be unpredictable
  • Only sold via auction sites and similar. No reputable retailers appear to stock these supplements, and they are not on sale from ordinary stores or shops

There is very little background information about the manufacture, the company behind it or even an accurate ingredients list for any of the four supplements.

What does iSDG Enzyme Pills claim to do?

With iSDG Enzyme Pills there are plenty of claims, and very few hard facts which make the whole brand look suspect.

Diet Enzyme Premium contains “232 vegetables and fruits enzymes” to “normalise your digestive cycle”

All the supplements are based on the 232 ingredients with added ingredients in order to improve additional functions.

Some ingredients are mentioned in the advertising on the box, but the spellings and English is not high quality. For example Coleus Forskoholii is named as “Coleus false coli extract“, which supposedly “promote fat burn and also prevent carbohydrate absorption”.

Beauty Premium, also referred to as Miki Enzyme Beauty, also contains the 232 enzymes as well as two odd ingredients named as “Birds nest“ and “Pearl powder which is a skin lightening preparation”.

Confusingly the iSDG products are known by a variety of different names, so it is hard to identify one product from the other because with the lurid packaging and pictures of fruit, they all look pretty much identical.

However the basic message of each supplement appears to tell you what you want to hear, and revolves around improving digestive health, getting slimmer, and lightening your skin. Claims are different depending on the advertiser. The skin lightening claim is mentioned in the Asian advertising for example, but not in the adverts aimed at the Western market.

None of this is impressive.

Does iSDG Enzyme Pills work?

We think it is unlikely. These supplements look a bit cheap and gimmicky to us, and without any adequate information regarding manufacture or ingredients, it is hard to see exactly what these supplements will do and whether there will be side effects.

The four products each contain the basic formula of 232 fruit and vegetable enzymes in unknown quantities. On top of this there are additional ingredients to target, sleep, weight loss, skin, or energy. These added components are named (and often misspelled), but the lack of quantity information is of deep concern.

The bottom line is that you will really have no idea what any of these supplements will do and whether they will work, or whether they will cause side effects or are even safe.

In our opinion, it is probably best to err on the side of caution and not to bother finding out. It is never a good idea to take supplements from unknown sources that contain unknown ingredients, as is the case here.

phentaslim bottle
The most popular consumer choice in 2021 is Phentaslim.

With a combination of proven ingredients, superb customer service and a 60-day money-back guarantee, Phentaslim is making big waves in the diet world.

Find out why thousands of people are choosing Phentaslim to achieve their weight loss goals, and why it's also the editor's top selection.

Read the Watchdog Phentaslim review here.

iSDG Enzyme Pills Ingredients

Serving size is equal to two pills.

The basic formula of each of the four supplements is as follows.

  • Composite plant cultivated sugar: Indigestible dextrin, sugar (brown sugar, oligosaccharide).
  • Fruits: Grape, peach, apple, oranges, strawberry, oyster, ususe, kiwi, kumquat, lemon, blueberry, akebi, yamamomo, pear, Banana, Primson, Pineapple, Banana, Primson, Yamaguchi, Sudachi, Kabosu, Orange, Avocado, tomatoes, Strawberries, prunes, dutch strawberries, Ashiya, pear, cam cam, acai, kuchananoshi, and lime.
  • Wild vegetables: Perilla, radish, cane, tomato, cabbage, egg, komatsuna, celery, spinach, chinensis, spinach, green pepper, bitter gourd, vitamin cream, pumpkin, carrots, burdock, broccoli, seri, misuba, milk, kel, barley young leaves, moroheiya, lotus root, turmeric, ginger, red meadow, turnip, onion, wasabi, mouth, potato, sweet potato, taro, garlic, Fukui, Mizuna, and Chisha.
  • Salad, vegetables: Purple cabbage, sunny lettuce, Asatsuki, green onions, cauliflower, edible chrysanthemums, bamboo shoots, zuiki, odor, white chestnuts, sugi, stews, zucchini, okra, lettuce, chicory, cassava, red turnip, Yakon, Paulica, Red Onion, Kokumin, Fukuinoto, Tara Bud, Bracken, Lucky, Nano Hana, White Asparagus, Cherry Blossom, Pecoros, mustard sprout, alfalfa, beets, purimo, radish, and hornwort.
  • Wild grasses: Psyllium, Kuwasaza, and Legumina.

On top of this basic enzyme formula, the various supplements contain additional specific ingredients. As with the rest of the ingredients list, there is no information regarding the quantities of each ingredient.

Diet Enzyme Premium (also referred to as Original Premium) contains;

  • Coleus false coli extract: Better known as coleus Forskoholii, this Asian plant extract contains a chemical called Forskolin which some evidence suggests may help fat metabolism. Source
  • L-carnitine: Amino acid which helps the body convert fat to energy.

Night Diet Enzymes

  • 4 Amino Acids: According to the advertising, this supplement contains 4 different amino acids. However they are not named so it is impossible to really know anything much about this supplement.

ISDG Beauty Enzymes

  • Birds Nest: Yes, it is a bird’s nest – best known in the Chinese delicacy bird nest soup and made from real birds’ nests built by birds (swifts) using their saliva. According to Chinese medicine it is good for health but bird saliva does not sound very appealing to most people. In addition it is very expensive and rare so does this cheap supplement really contain this prized ingredient?
  • Pearl Powder: Made from freshwater pearls crushed into powder and believed to help stimulate and improve skin. Used extensively in China. Source

Exhilarating Enzyme: Sometimes referred to as Soukai Enzyme Supplement Premium.

  • Lactobacillus Bifidus BR-108: Made by Combi corporation, which appears to be a Tokyo based supplements company. Lactobacillus Bifidus is a probiotic, meaning it contains “good bacteria“ which may help digestive heath.

iSDG Enzyme Pills Side Effects

It’s hard to say just what any of these supplements will do. However potential side effects may include, amongst other effects,

  • Diarrhoea
  • Abdominal discomfort
  • Headaches
  • Allergic reaction


Not suitable for individuals under 18. Avoid if you are pregnant or breast feeding. Avoid if you have any underlying health issues, and cease use if you experience any side effects.

iSDG Enzyme Pills Customer Feedback

There are only five customer reviews posted on Amazon, and none of these are very insightful.

It helps my digestion!

so so

I broke out so badly after taking this pill. Returned it.


So far it’s working….need to take it longer to see if it’s really working

iSDG Enzyme Pills Money-Back Guarantee

There is no money-back guarantee on offer.

Where To Buy iSDG Enzyme Pills

If you are based in the USA, the easiest way to buy iSDG supplements is via Amazon USA. We have also seen Night Enzyme and Beauty Enzyme on sale via Amazon UK.

Customers based in South Asia can buy via Lazada.

Watchdog Verdict

We are not impressed by iSDG Enzyme Pills. Although we like the concept of enzymes and the fruit and vegetable enzyme ingredients, the fact that there is practically no real product information about the contents of the pills is of serious concern. These supplements do not translate well to Western use. Most of us have no urge to take bird saliva or crushed pearls in supplement form, and although these are well known in Asia, there is no evidence that they will do anything at all for your health or your wellbeing.

In addition, we do not trust iSDG the company behind the supplements. There is no proper website, and zero information about manufacture and ingredients quantities. This supplement range is showing up on sites such as eBay, but is not stocked by any reputable online retailers, making the whole set up look even more untrustworthy.

The bottom line is that we would not take iSDG Enzymes ourselves, so we would never recommend this supplement range to the Watchdog readers.

How does iSDG Enzyme Pills compare to Phentaslim?

CriteriaiSDG Enzyme Pills ComparisonPhentaslim comparison
Clinically Proven Ingredients
Side Effect Free
Positive Customer Reviews
24/7 Support
Money-back Guarantee

Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

Have Your Say

Get the conversation started by leaving your comments using the form above.

    Add your comment

    We'd love to get your opinion. Please keep it clean and stay on topic, no spamming. Comments are moderated before being made live. Your email address will not be published.
    We cannot give advice about medical conditions or prescription drugs. Please direct specific medical questions to your doctor.

    This site uses Akismet to reduce spam. Learn how your comment data is processed.