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LA-3 (Live Cell Research)

Updated May 20, 2019.
Published Jan 7, 2017.

LA-3 is a weight-loss product that works by activating the body’s natural store of the AMPK enzyme. There is only one active ingredient in LA-3 (i.e. one that has been included in a significant quantity), which is gynostemma. LA-3 claims to help you lose belly fat, clear “brain fog”, and enjoy a new youthful burst of energy. We uncover the facts so that you can make an informed decision about whether to try this supplement or not.

Pros

  • Excellent money-back guarantee
  • Uses a new and interesting approach to weight loss

Cons

  • Reviews and the ingredients list suggest the product does not work
  • Relatively expensive
  • Side effects have been reported
LA 3 Live Cell Research
Weight loss supplements are a mixed breed, and different kinds of products approach the topic from wildly different angles. Some ingredients claim to act as “fat burners” that literally remove fat deposits from the body, whereas others claim to act as appetite suppressants, effectively helping dieters to avoid putting on weight in the first place. In recent years, a brand new approach to the problem has reared its head, focusing its efforts on activating the body’s natural stores of the mysterious and exciting AMPK enzyme.

Below we take an in-depth look into LA-3, to see whether this AMPK activator can help customers lose belly fat, clear “brain fog”, and enjoy a new youthful burst of energy.

LA-3 Overview

What you need to know about LA-3

LA-3 is a weight loss supplement that works by activating the body’s stores of the AMPK enzyme, an intercellular signalling pathway that’s associated with youth, fitness and healthy fat levels. The product appears to be identical to another product called Active-PK, which is sold and marketed by a subdivision of the same manufacturer (LCR Health). Both products claim to be able to target stubborn belly fat in particular, as well as limit some of the negative effects of aging (such as “brain fog” and general fatigue).

LA-3 is produced and sold by Live Cell Research, a US-based manufacturer that sells a range of health, diet and anti-aging supplements. Live Cell Research projects a professional and knowledgeable image on its official website, and backs up all products with an exceptional 90-day money-back guarantee. The company also seems to have an interest in new medical breakthroughs, typically marketing products that claim to represent the latest in medical technology (whether they have been proven to be effective or not).

What are the side effects of LA-3?

Customer reviews suggest that side effects are not uncommon whilst using LA-3, with most adverse effects likely being the result of using gynostemma leaf extract. Gynostemma may sometimes cause nausea, vomiting and more frequent bowel movements.

How much does LA-3 cost?

On the official LCR Health website, one 60-capsule bottle (or a one-month supply) costs $46.99 plus $3.95 in shipping and handling. Discounts are available for bulk purchases; 3 bottles of LA-3 costs $117 and 6 bottles costs $216. Both of the bulk purchase options come with free shipping and handling. Those hoping to find better deals on 3rd party websites are out of luck, as LA-3 is unfortunately only available to buy from the official LCR Health website.

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LA-3 Key Features

LA-3 is a weight loss product that works by activating the body’s natural store of the AMPK enzyme. The AMPK enzyme (which stands for 5’ adenosine monophosphate-activated protein kinase) has been found to be positively associated with a number of positive traits, including youthful energy, healthy weights, and strong exercise performance. The theory claims that supplements may be able to activate and effectively boost AMPK levels, delivering these interesting benefits as a result.

LA-3 Key Points

  • Manufactured by Live Cell Research
  • Contains 60 capsules per bottle
  • Weight loss product that works by activating the AMPK enzyme

This AMPK-activating product is produced and sold by Live Cell Research, a supplement manufacturer based in Los Angeles. Live Cell Research have a kind of “medical” theme dominating their website and advertising materials, and are refreshingly committed to marketing products in a relatively straightforward manner that is free from extreme exaggeration. Their customer service standards aren’t bad either, with all purchases protected by an impressive 90-day money-back guarantee. The company can be contacted via the contact details supplied on their official website.

How to Take LA-3

The directions for use are as follows:

Just take two capsules with a glass of water, either with food or on an empty stomach. It is not necessary to refrigerate LA-3, although doing so will not impact its effectiveness.

Live Cell Research’s customer service standards aren’t bad either, with all purchases protected by an impressive 90-day money-back guarantee. The company can be contacted via the contact details supplied on their official website.

LA-3 Concerns

  • Ingredient quantities are often far too low to be effective
  • It is not at all clear whether the product works as advertised
  • Customer reviews are mixed on whether this product works

What does LA-3 claim to do?

LA-3 claims to help dieters to lose weight and belly fat through its ability to activate the AMPK enzyme. The AMPK enzyme is described as the body’s “master switch” on the Live Cell Research website; when activated, the AMPK enzyme is said to instruct the body to stop storing fat and instead work to convert it to energy.

On the product page’s FAQ section, LA-3 is also said to be useful for customers experiencing “brain fog”, fatigue, or a reduction in physical energy (perhaps implying that this formula can help deal with these issues). The full list of benefits mentioned on the Live Cell Research website are:

  • More energy
  • Clearer thinking
  • Decreased abdominal fat
  • A stronger, healthier body

Does LA-3 work?

The benefits of AMPK activation are still not fully understood by the scientific community and most of the studies that look into it are both new and limited to animal trials. Although we know that low AMPK activation is associated with obesity, old age and physical weakness, it isn’t clear whether supplements can limit or reverse this effect at all. The best recommendation may simply be to eat better and exercise more.

In any case, this product does not hold up as a particularly impressive approach to AMPK activation. Two out of the three ingredients used have been included in far too low quantities to be effective, and the only remaining effective ingredient (gynostemma) has never been tested on humans. Gynostemma has also never been found to affect weight loss and is likely far less effective than other weight loss ingredients out there.

Overall, customer reviews and our general understanding of AMPK activation lead us to believe that this product is likely weakly effective at best and totally ineffective at worst. It may impact “brain fog” somewhat but few customers claim that it helped them to lose weight.

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LA-3 Ingredients

The three ingredients included in LA-3 are listed below. The ingredient quantities listed below are correct for 2 capsules.

  • Gynostemma Pentaphyllum leaf extract (ActivAMP) 450mg: This plant has been found to have beneficial anti-diabetic effects, many of which are still being explored. It has been found to raise AMPK levels in rats, and is thought by some researchers to be a mild prophylactic. Although found to be effective at reducing the blood glucose levels (and body weight) of diabetics, gynostemma has never been tested on otherwise-healthy subjects.
    Source: https://examine.com/supplements/gynostemma-pentaphyllum/
  • Quercetin dihydrate 100mg: Known for AMPK activation, quercetin has antioxidant and anti-carcinogenic properties. It tends not to produce dramatic or consistent effects when tested on humans when compared to in-vitro tests, and has never been linked with any weight loss effects. In any case, the dose included in this product is far too low to be effective.
    Source: https://examine.com/supplements/quercetin/
  • Berberine HCI 100mg: Berberine is used to slightly reduce blood sugar levels in those with diabetes, and has been linked with reducing cholesterol. It is also known to activate AMPK enzymes, which has then been linked with fat loss effects and anti-aging effects in tests. Despite its potential utility for a product like this, the dosage included is far, far too low to be effective.
    Source: http://www.webmd.com/vitamins-supplements/ingredientmono-1126-berberine.aspx?activeingredientid=1126&activeingredientname=berberine

LA-3 Side Effects

There is only one active ingredient in LA-3 (i.e. one that has been included in a significant quantity), which is gynostemma. Gynostemma extract is considered to be generally safe, but may sometimes cause nausea and more frequent bowel movements.

Experiencing nausea appears to be relatively common whilst using this product (or its identical sister product, Active-PK), and multiple customer reviews mention feeling nauseous or even vomiting. We recommend exercising caution before trying it out, especially if you are already ill.

Caution: Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

LA-3 Customer Feedback

Most of the customer reviews we found online were generally split down the middle; some customers report life-changing, positive effects, and others report huge disappointment. Weight loss results were relatively rare, with most positive comments being directed towards LA-3’s ability to reduce “brain fog”. Some negative reviews highlighted serious side effects such as nausea or vomiting.

I bought this product for the reduced belly fat that they stated highly in their advertisement. I took the product for three months with NO loss of belly fat at all. They claim that this could be achieved without exercise. I did feel that I had an increased energy level and possibly better memory and less brain fog. For the price, I don’t feel it was at all worth it. I feel there are probably other products that cost less that could be purchased for the energy and less brain fog.

I ordered this product, and all it did was cause diarrhea. I tried to get a refund but wasn’t aware that it had to be 90 days from the day you purchased, not when you first started taking it. I tried to get a refund and was told I didn’t respond in time even though I have a few days left. It amazes me how they always twist it in their favor.

I ordered a six-month supply because I was leaving the country for several months. I have been taking this product as suggested (two a day) for the past two and a half months and I have not noticed any difference. The claims of INCREASED ENERGY, no noticeable difference. DECREASED APPETITE, no noticeable difference. DECREASE IN BELLY FAT, I am actually gaining weight. The only thing I can say about this product is take a placebo; it does the same thing.

Beautiful, clean, no side effects, instant activating metabolism. Wow. I have been on these capsules for two weeks taking two a day for ten days, and I lost 1.4 kilos. I am taking four per day now, and it is only the early days for weight loss results, and I’m only targeting belly fat. With no hesitations, I bought a one-year supply. My name for LA-3 is “the holy grail” and it should be marketed globally so everyone can try out. I just turned 60, assuming my life was physically over, and thank you to whoever created LA-3, I’m getting a new lease on life.

I feel 15 years younger, both mentally and physically! I want more of this product. I’ve been using it for six months.

I saw an increase of energy in the second day, started losing body fat after the first week, had no more foggy memory, and I sleep better. I am in the fourth week of taking them, and I love it. I would recommend it to anyone.

LA-3 Money-Back Guarantee

Live Cell Research offers a generous and comprehensive money-back guarantee on all purchases. All products purchased through the official website can be returned within 90 days for a full refund. To quote the website:

At Live Cell Research, we take great pride in our products. We use only the best ingredients. We proudly keep all of our manufacturing and customer service in Southern California. We maintain the highest manufacturing standards in the industry, exceeding cGMP guidelines. As such, all of our products come with a 90 day money-back guarantee. You can return your order for any reason. We will gladly refund your money, no questions asked.

Where To Buy LA-3

LA-3 is only available to buy from the official Live Cell Research website. One 60-capsule bottle of LA-3 costs $46.99 plus shipping and handling (an additional $3.95). Bulk-buy options are cheaper per bottle and remove all shipping and handling charges – 3 bottles cost $117 and 6 bottles cost $216.

Watchdog Verdict

The theory behind AMPK activation is ultimately very new and somewhat poorly understood, and the jury is still out as to whether supplements like these can really help dieters to lose weight. The problem appears to be related to how we understand cause-and-effect; just because high AMPK levels are associated with healthy weights, youth and fitness, that does not necessarily mean that artificially activating the enzyme using supplements will always lead to those outcomes!

Even if the theory behind AMPK activation were watertight, this product still suffers from a number of issues. Like its identical sister-product Active-PK, LA-3 features two ingredients that are going to be useless in the current formula, as their ingredient quantities are far too low. Customer reviews suggest that positive results are far from guaranteed, with many customers reporting wildly different outcomes. After studying the reviews, we still believe that it is entirely possible that LA-3 is doing nothing at all.

All of this is a shame, as we generally like the manufacturer. Live Cell Research’s 90-day money-back guarantee is amongst the best in the industry, and the company generally seems to be concerned with customer satisfaction and product quality. Unfortunately, LA-3 represents a rare miss, and one that we cannot endorse.

We would not recommend LA-3 to our readers.

How does LA-3 (Live Cell Research) compare to Phentaslim?

Criteria LA-3 (Live Cell Research) Comparison Phentaslim comparison
Clinically Proven Ingredients
Side Effect Free
Positive Customer Reviews
24/7 Support
Money-back Guarantee
FREE SHIPPING

Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

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75 comments on 'LA-3 (Live Cell Research)'

  1. Hi Rachel. Here is one for you to “get to the bottom of”. I used LA-3 for 2 years with no noticeable effect. Quit it with no negative effect. Now what appears to be the same product (similar ingredients, similar promotion, similar claims, similar looking capsule) is being promoted by Princeton Nutrients as “Master Switch”. Very similar story for Vital Stem from LCR and Omega Stem from Princeton Nutrients with a similar time delay between promotions. Can you find out what is going on here?

    1. Hi Murray, my name is Taylor with LCR Health. We are in no way affiliated with Princeton Nutrients. There may be similar products on the market but we fully stand by our products. Please don’t hesitate to reach out to me at [email protected] with questions, concerns, or comments.

  2. I started using the LA-3 product in late November 2017. I’m 63 years old. I go to the gym 3 to 4 times a week and I even quit alcohol for 1/2 of the 90 day trial I was going to give this product. I stopped using it after 70 days because it did nothing! Waste of my money.
    I received a partial refund and I’m still attempting to get the rest of my money.

    1. Hi John, my name is Taylor with LCR Health. I’m very sorry to hear that this was your experience with LA-3. We understand that everybody is different so this product may work well for some but not others. Please email me at [email protected] and I will provide you with a full refund.

  3. Hi Prentiss, please consult your primary physician as soon as possible if you are experiencing these symptoms! Are you experiencing this while taking LA-3? If you are, please e-mail me directly [email protected] and I can issue you a full refund if you are interested! Take care!

  4. I have been using LA-3 for over a year now, and am trying to provide a review that is honest and not based on post-purchase rationalization to influence my comments. What I can say is that I have done nothing to change my eating (average to poor) and exercise (little to no) habits, and my weight has stayed within the same 5 pound range over that time (I weigh myself at least once a week). That includes through the holidays. Blood work has been the same too, with just slight drops in cholesterol and triglyceride levels. I suspect I would see more improvement if I can resolve issues with sleep apnea since that has a huge negative impact on all three of the conditions that AMPK is supposed to help with (metabolic response , mental acuity and energy levels). My energy levels and mental sharpness are hard to judge in comparison, but I would say my focus has gotten a little better over time (subjective measure). It would also help if I improved my diet and exercise routine, but I have inadvertantly been performing a controlled test with the only change being the addition of LA-3 AMPK supplement.
    I do believe if I am able to reduce/eliminate sleep apnea that that alone would also improve all three. I wouldn’t say LA-3 has provided drastic results for me, but I don’t expect drastic, I expect small incremental improvements, and I know that many people respond differently to different supplements based on genetics, diet, exercise habits, consistency in use, and so on. Don’t go out there looking for a fountain of youth pill….you won’t find it, but maybe something that slows the process ever so slightly? I’ll take that! If I could give this 3.5 stars I would, because I think it deserves more than 3 stars, but 4 might be too much of a recommendation of the product. Temper expectations.

  5. I am using it and I find it does exactly what they say it will on the card they sent with it. Everything they said would happen did in the order they said it would. I have had no side affects and I take the tablets two times a day.

    I have seen changes in my body just as they said I would, I also eat right and walk. But I like the product and think it is well worth the money.

  6. I was referred from a friend who lost 110 lbs over a year because they felt satiated at the right time during a meal. After 2 months, this is also happening with me. Therefore, their claims are working so which is the scam, their claims or your shallow review?

  7. I checked out Phentaslim and noticed I get many of the ingredients from vitamins proscribed by my physician, or from the other Live Cell Research products. So if I stick with the supplements I already get from LCR it would be redundant to use a product such as Phentaslim.
    Products I currently use from Live Cell Research include LA-3, Midogen, NR-1, Cerastim, GP-slim, adult probiotics. I also take vitamin B12, D3,. I also take Boron complex, Prosttaid, and calcium, and Magnesium as a topical application all from Piping Rock. I take krill Oil as well. I have no problem with LA-3 in the 6 months I have been taking it, and I am well aware of the fact that every supplement can have varying effects on difrent individuals. My doctor is happy with my health indicators sense I have started taking the Live Cell Research products, I am 62 years old, I am a cancer survivor of about 13 years now, oncology once told me I could expect to live a good five years. So if my doctor is happy with my overall health at this time, then I am more inclined to except his opinion than be swayed by that of a lawyer, no disrespect intended.

  8. My mother was hospitalized for triple pneumonia and was diagnosed at that time with COPD. She had been a smoker since she was 16 years old and was about 70 years at diagnosis, so she had been smoking for about 55 years. We were so well educated about the damage smoking had done to her lungs,and we know there is no cure to COPD ,thank GOD for leading us to GOOD HEALTH HERBS HOME,please don’t ignore this post is real, Dr George(Good health herbs home) is a real herbal Doctor ,he cured my mother of COPD,she was totally cured within 5 weeks of usage. Dr George (Good health herbs home) herbal medicine for COPD has no side effect,it works like a miracle,please viewers out there that have any deadly disease,please don’t fail contact Dr George via email

  9. CURED

    My mother was hospitalized for triple pneumonia and was diagnosed at that time with COPD. She had been a smoker since she was 16 years old and was about 70 years at diagnosis, so she had been smoking for about 55 years. We were so well educated about the damage smoking had done to her lungs,and we know there is no cure to COPD ,thank GOD for leading us to GOOD HEALTH HERBS HOME,please don’t ignore this post is real, Dr George(Good health herbs home) is a real herbal Doctor ,he cured my mother of COPD,she was totally cured within 5 weeks of usage. Dr George (Good health herbs home) herbal medicine for COPD has no side effect,it works like a miracle,please viewers out there that have any deadly disease,please don’t fail contact Dr George via email drgeorge @ goodhealthherbshome .com , info @ goodhealthherbshome . com..or website goodhealthherbshome . com ..

  10. Jean
    My husband has been taking LA-3 for three months and I suddenly noticed his belly fat was gone and he said he thought he had lost 20lb +. He was 206 and decidedly to weigh himself and we discovered he now was at 175. Remarkable!!!! No explanation except it worked and he has a ton more energy and feels 100% better. He is 77yrs old. You can’t tell me it doesn’t work I have seen the results for myself.

  11. Dr George(Good health herbs home) is a real herbal Doctor ,he cured my mother of COPD,she was totally cured within 5 weeks of usage. Dr George (Good health herbs home) herbal medicine for COPD has no side effect,it works like a miracle,please viewers out there that have any deadly disease,please don’t fail contact Dr GeorgE

  12. My mother was hospitalized for triple pneumonia and was diagnosed at that time with COPD. She had been a smoker since she was 16 years old and was about 70 years at diagnosis, so she had been smoking for about 55 years. We were so well educated about the damage smoking had done to her lungs,and we know there is no cure to COPD ,thank GOD for leading us to GOOD HEALTH HERBS HOME,please don’t ignore this post is real,

  13. My husband and I started taking in Aug 2017. I needed something to jump start my body into loosing hidden body fat. I had 90 lbs to loose to be at my healthiest weight. I am 64 and my husband is 70. I started out with a food program and I did loose 20 pounds, then I stalled no matter what I did. I maintained a 1200 calorie diet, low fat, normal protein requirements with good fruits & vegetables and a lot of water. Then I started a prebiotic and probiotic program which helped me loose 1/2 to 1 lbs a week again, but my hunger levels were off the chart. When we started LA-3, I began to loose 2 lbs. in the first week and have maintained that weight loss each week. My husband took about 2 weeks to adjust because he felt some nausea. So I had him take it at the start of breakfast, he has had no sideffects since. An amzing has happened. When ever we get Respiratory infections they hang on. Not now. Not only do we have more energy and are healing faster, but we are more alert and have better endurance. My hubby has COPD from severe asthma over the years, for him to get over an infection in a week is amazing. He doesn’t hesitate taking it at all now. We are going to continue to take it! We are living proof it does work. As a nurse I can tell you we do not all have the same bodies or health issues. It has taken me 3 years thru trial and error to find what works. Ask questions and do your homework!

  14. Good morning. LA-3 just started 8/20 – looking forward to more energy and weight loss. Just 2 capsules with a full glass or more of water. Is there a facebook group for this product?

    1. Hi there! Unfortunately, we do not ship to Nigeria. I am so sorry for the inconvenience. As we continue to expand, we may continue expanding our shipping destinations. Keep a lookout!

  15. My life partner and I used LA-3 for 6 months as directed. My partner has NASH so we questioned his cancer Doctor and she had no problem with it. We both lost an average of 10 pounds a week and really felt better with considerable more energy. Once we stopped, we both got lazier and more hungry. My partner had another liver sonogram done after we had just about completed the last bottle and his liver had actually regenerated itself somewhat. I don’t know if LA-3 had anything to do with it or not but, we are going to try another round.

  16. I have been taking this product for 3 months. I have not lost any weight, nor any inches from my waist and abdomen area. I have experienced some bloating, mostly joint and muscle pain going into the 3 month on this product. I tossed the rest in the trash, where it belongs. This product did not work for me, and I followed the directions to the “T”. I actually feel it caused me more harm than good. I do not recommend this product.

    1. Hi Cathy;
      I don’t understan your remarks, please explain. Why would you toss LA3 into the trash when you can get your money back as advertized? I would appreciate your answer as I really would like to order it. Did they refused to give a refund or what was the actual problem? Maybe you could help me to make up my mind to order it or not.
      best regards,
      Tina

    2. Hi Cathy, I’m Aurora from Live Cell Research. I am so sorry to hear that you did not experience all of the benefits you had expected when taking this product. While a majority of our customers have experienced the amazing benefits of LA-3, we do understand it may not work for everyone. Our standard return policy is to send us back the bottles you did not use, and then we would issue you a full refund. But I would be more than happy to issue you a full refund, regardless of how long it’s been and no need to send anything back. Please know that this is a one time exception. If you are interested, please e-mail me at [email protected]. Take care!