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LA-3 (Live Cell Research)

Weight-loss supplements are a mixed breed, and different kinds of products approach the topic from wildly different angles. Some ingredients claim to act as “fat burners” that literally remove fat deposits from the body, whereas others claim to act as appetite suppressants, effectively helping dieters to avoid putting on weight in the first place. In recent years, a brand new approach to the problem has reared its head, focusing its efforts on activating the body’s natural stores of the mysterious and exciting AMPK enzyme.

Below we take an in-depth look into LA-3, to see whether this AMPK activator can help customers lose belly fat, clear “brain fog” and enjoy a new youthful burst of energy.

LA-3 (Live Cell Research) Pros

  • Excellent money-back guarantee
  • Product uses a new and interesting approach to weight loss

LA-3 (Live Cell Research) Cons

  • The evidence of reviews and the ingredients list suggest the product does not work
  • Product is relatively expensive
  • Side effects have been reported
Watchdog Rejected

LA-3 (Live Cell Research)

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What You Need To Know About LA-3 (Live Cell Research)

LA-3 is a weight-loss supplement that works by activating the body’s stores of the AMPK enzyme, an intercellular signalling pathway that’s associated with youth, fitness and healthy fat levels. The product appears to be identical to another product called Active-PK, which is sold and marketed by a subdivision of the same manufacturer (LCR Health). Both products claim to be able to target stubborn belly fat in particular, as well as limit some of the negative effects of aging (such as “brain fog” and general fatigue).

LA-3 is produced and sold by Live Cell Research, a US-based manufacturer that sells a range of health, diet and anti-aging supplements. Live Cell Research projects a professional and knowledgeable image on its official website, and backs up all products with an exceptional 90-day money-back guarantee. The company also seems to have an interest in new medical breakthroughs, typically marketing products that claim to represent the latest in medical technology (whether they have been proven to be effective or not).

What Are The Side Effects Of LA-3 (Live Cell Research)?

Customer reviews suggest that side effects are not uncommon whilst using LA-3, with most adverse effects likely being the result of using gynostemma leaf extract. Gynostemma may sometimes cause nausea, vomiting and more frequent bowel movements.

How Much Does LA-3 (Live Cell Research) Cost?

On the official LCR Health website, one 60-capsule bottle (or a one-month supply) costs $46.99 plus $3.95 in shipping and handling. Discounts are available for bulk purchases; 3 bottles of LA-3 costs $117 and 6 bottles costs $216. Both of the bulk purchase options come with free shipping and handling. Those hoping to find better deals on 3rd party websites are out of luck, as LA-3 is unfortunately only available to buy from the official LCR Health website.

Our Verdict On LA-3 (Live Cell Research)

The theory behind AMPK activation is ultimately very new and somewhat poorly understood, and the jury is still out as to whether supplements like these can really help dieters to lose weight. The problem appears to be related to how we understand cause-and-effect; just because high AMPK levels are associated with healthy weights, youth and fitness, that does not necessarily mean that artificially activating the enzyme using supplements will always lead to those outcomes!

Even if the theory behind AMPK activation were watertight, this product still suffers from a number of issues. Like its identical sister-product Active-PK, LA-3 features two ingredients that are going to be useless in the current formula, as their ingredient quantities are far too low. Customer reviews suggest that positive results are far from guaranteed, with many customers reporting wildly different outcomes. After studying the reviews, we still believe that it is entirely possible that LA-3 is doing nothing at all.

All of this is a shame, as we generally like the manufacturer. Live Cell Research’s 90-day money-back guarantee is amongst the best in the industry, and the company generally seems to be concerned with customer satisfaction and product quality. Unfortunately, LA-3 represents a rare miss, and one that we cannot endorse.

We would not recommend LA-3 to our readers.

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LA-3 (Live Cell Research) Review

LA-3 is a weight-loss product that works by activating the body’s natural store of the AMPK enzyme. The AMPK enzyme (which stands for 5’ adenosine monophosphate-activated protein kinase) has been found to be positively associated with a number of positive traits, including youthful energy, healthy weights and strong exercise performance. The theory claims that supplements may be able to activate and effectively boost AMPK levels, delivering these interesting benefits as a result.

LA-3 (Live Cell Research) Facts

  • Manufactured by Live Cell Research
  • Contains 60 capsules per bottle
  • Weight loss product that works by activating the AMPK enzyme

This AMPK-activating product is produced and sold by Live Cell Research, a supplement manufacturer based in Los Angeles. Live Cell Research have a kind of “medical” theme dominating their website and advertising materials, and are refreshingly committed to marketing products in a relatively straightforward manner that is free from extreme exaggeration. Their customer service standards aren’t bad either, with all purchases protected by an impressive 90-day money-back guarantee. The company can be contacted via the contact details supplied on their official website.

How to Take LA-3 (Live Cell Research)

The directions for use are as follows:

Just take two capsules with a glass of water, either with food or on an empty stomach. It is not necessary to refrigerate LA-3, although doing so will not impact its effectiveness.

LA-3 (Live Cell Research) Concerns:

  • Ingredient quantities are often far too low to be effective
  • It is not at all clear whether the product works as advertised
  • Customer reviews are mixed on whether this product works

What Does LA-3 (Live Cell Research) Claim To Do?

LA-3 claims to help dieters to lose weight and belly fat through its ability to activate the AMPK enzyme. The AMPK enzyme is described as the body’s “master switch” on the Live Cell Research website; when activated, the AMPK enzyme is said to instruct the body to stop storing fat and instead work to convert it to energy.

On the product page’s FAQ section, LA-3 is also said to be useful for customers experiencing “brain fog”, fatigue, or a reduction in physical energy (perhaps implying that this formula can help deal with these issues). The full list of benefits mentioned on the Live Cell Research website are:

  • More energy
  • Clearer thinking
  • Decreased abdominal fat
  • A stronger, healthier body

Does LA-3 (Live Cell Research) Work?

The benefits of AMPK activation are still not fully understood by the scientific community and most of the studies that look into it are both new and limited to animal trials. Although we know that low AMPK activation is associated with obesity, old age and physical weakness, it isn’t clear whether supplements can limit or reverse this effect at all. The best recommendation may simply be to eat better and exercise more.

In any case, this product does not hold up as a particularly impressive approach to AMPK activation. Two out of the three ingredients used have been included in far too low quantities to be effective, and the only remaining effective ingredient (gynostemma) has never been tested on humans. Gynostemma has also never been found to affect weight loss and is likely far less effective than other weight loss ingredients out there.

Overall, customer reviews and our general understanding of AMPK activation lead us to believe that this product is likely weakly effective at best and totally ineffective at worst. It may impact “brain fog” somewhat but few customers claim that it helped them to lose weight.

What Are The Ingredients of LA-3 (Live Cell Research)?

The three ingredients included in LA-3 are listed below. The ingredient quantities listed below are correct for 2 capsules.

  • Gynostemma Pentaphyllum leaf extract (ActivAMP) 450mg: This plant has been found to have beneficial anti-diabetic effects, many of which are still being explored. It has been found to raise AMPK levels in rats, and is thought by some researchers to be a mild prophylactic. Although found to be effective at reducing the blood glucose levels (and body weight) of diabetics, gynostemma has never been tested on otherwise-healthy subjects.
    Source: https://examine.com/supplements/gynostemma-pentaphyllum/
  • Quercetin dihydrate 100mg: Known for AMPK activation, quercetin has antioxidant and anti-carcinogenic properties. It tends not to produce dramatic or consistent effects when tested on humans when compared to in-vitro tests, and has never been linked with any weight loss effects. In any case, the dose included in this product is far too low to be effective.
    Source: https://examine.com/supplements/quercetin/
  • Berberine HCI 100mg: Berberine is used to slightly reduce blood sugar levels in those with diabetes, and has been linked with reducing cholesterol. It is also known to activate AMPK enzymes, which has then been linked with fat loss effects and anti-aging effects in tests. Despite its potential utility for a product like this, the dosage included is far, far too low to be effective(!)
    Source: http://www.webmd.com/vitamins-supplements/ingredientmono-1126-berberine.aspx?activeingredientid=1126&activeingredientname=berberine

Does LA-3 (Live Cell Research) Have Any Side Effects?

There is only one active ingredient in LA-3 (i.e. one that has been included in a significant quantity), which is gynostemma. Gynostemma extract is considered to be generally safe, but may sometimes cause nausea and more frequent bowel movements.

Experiencing nausea appears to be relatively common whilst using this product (or its identical sister product, Active-PK), and multiple customer reviews mention feeling nauseous or even vomiting. We recommend exercising caution before trying it out, especially if you are already ill.

Keep out of reach of children. Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Are There Any Customer Reviews For LA-3 (Live Cell Research)?

Most of the customer reviews we found online were generally split down the middle; some customers report lifechanging, positive effects, and others report huge disappointment. Weight loss results were relatively rare, with most positive comments being directed towards LA-3’s ability to reduce “brain fog”. Some negative reviews highlighted serious side effects such as nausea or vomiting.

I bought this product for the reduced belly fat that they stated highly in their advertisement. I took the product for three months with NO loss of belly fat at all. They claim that this could be achieved without exercise. I did feel that I had an increased energy level and possibly better memory and less brain fog. For the price, I don’t feel it was at all worth it. I feel there are probably other products that cost less that could be purchased for the energy and less brain fog.

I ordered this product, and all it did was cause diarrhea. I tried to get a refund but wasn’t aware that it had to be 90 days from the day you purchased, not when you first started taking it. I tried to get a refund and was told I didn’t respond in time even though I have a few days left. It amazes me how they always twist it in their favor.

I ordered a six-month supply because I was leaving the country for several months. I have been taking this product as suggested (two a day) for the past two and a half months and I have not noticed any difference. The claims of INCREASED ENERGY, no noticeable difference. DECREASED APPETITE, no noticeable difference. DECREASE IN BELLY FAT, I am actually gaining weight. The only thing I can say about this product is take a placebo; it does the same thing.

Beautiful, clean, no side effects, instant activating metabolism. Wow. I have been on these capsules for two weeks taking two a day for ten days, and I lost 1.4 kilos. I am taking four per day now, and it is only the early days for weight loss results, and I’m only targeting belly fat. With no hesitations, I bought a one-year supply. My name for LA-3 is “the holy grail” and it should be marketed globally so everyone can try out. I just turned 60, assuming my life was physically over, and thank you to whoever created LA-3, I’m getting a new lease on life.

I feel 15 years younger, both mentally and physically! I want more of this product. I’ve been using it for six months.

I saw an increase of energy in the second day, started losing body fat after the first week, had no more foggy memory, and I sleep better. I am in the fourth week of taking them, and I love it. I would recommend it to anyone.

Does LA-3 (Live Cell Research) Offer a Money-Back Guarantee?

Live Cell Research offers a generous and comprehensive money-back guarantee on all purchases. All products purchased through the official website can be returned within 90 days for a full refund. To quote the website:

At Live Cell Research, we take great pride in our products. We use only the best ingredients. We proudly keep all of our manufacturing and customer service in Southern California. We maintain the highest manufacturing standards in the industry, exceeding cGMP guidelines. As such, all of our products come with a 90 day money-back guarantee. You can return your order for any reason. We will gladly refund your money, no questions asked.

Where Can I Buy LA-3 (Live Cell Research)?

LA-3 is only available to buy from the official Live Cell Research website. One 60-capsule bottle of LA-3 costs $46.99 plus shipping and handling (an additional $3.95). Bulk-buy options are cheaper per bottle and remove all shipping and handling charges – 3 bottles cost $117 and 6 bottles cost $216.

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Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

72 comments on “LA-3 (Live Cell Research)”

  1. dawn says:

    I’m going to ask my Dr if he believes it will help. it would be a miracle if it does I want to try it so bad. I have bought so many things in the past few results so I’m a little undecided with the price but I like the explanation given why it works so I may bite the bullet

    1. Aurora says:

      Hi Dawn, I’m Aurora from Live Cell Research. I agree with your suggestion about consulting your Doctor first! If your Doctor gives you the green light, I would love to assist you with any questions you may have about the product or the ordering process! Please feel free to e-mail me at aurora@livecellresearch.com! I look forward to hearing from you!

  2. Bob says:

    I am always skeptical of any online presentation that take over 25 minutes of bs before they tell you what they are selling and what it cost.
    Below is the three main ingredients in LCR LA3 or Active PK that you can buy on your own for much less as below amounts is equivalent to a 2 months supply all for about $30 on herb website of your searching like iHerb:
    Solaray, Berberine, Special Formula, 60 Veggie Capsules
    Item Price: $9.22
    Solaray, Mega Quercetin, 1200 mg, 60 Veggie Caps
    Item Price: $9.84
    Paradise Herbs, Jiaogulan, 60 Veggie Caps
    Item Price: $10.00

    1. Aurora says:

      Hi Bob! I am so sorry to hear that you were swayed from trying our product after watching our informational presentation. We do understand that a customer could purchase three separate products but the convenience of purchasing an all-in-one product like LA-3 is much more manageable and convenient. Also, I cannot verify the ingredients used in the products you listed but the ingredients found in LA-3 are high-quality ingredients that have been tested for purity, safety and potency. It is priced this way to reflect this. I would be more than happy to send you a free bottle of LA-3 so you can make a more accurate assessment about our product. If you are interested, you can e-mail me at aurora@livecellresearch.com. I look forward to hearing from you!

  3. Arlene Jardine says:

    I have been taking LA-3 for one month, however, my weight loss is not that much but the most amazing thing to me is that I have so much more energy and I have been having back pain from a herniated disk which has completely abated. I can only attribute this to LA-3 because I am not taking anything else, it must have brought down the inflammation. There were nights when I turned in bed and the pain jolted me from my sleep. I am now walking longer and doing more reps.

    1. Aurora says:

      Hi Arlene! I am so happy to hear that you are experiencing more energy and have less pain since taking LA-3! This is great news! Thank you so much for taking the time to leave a review!

  4. Ellen says:

    I just was looking at the same product, same company – but now sold as ACTIVE-PK. Somehow – I want to try it but seeing it change it’s name makes me wonder why. I’ll do more research

  5. Markey says:

    I am an older woman, not overweight, but have a large belly that never goes
    away. Been examined and MD. says it is belly fat. I cannot take any medication that will unnaturally raise my heart rate. I would love to try
    LA3, but need to hear from you first. Please let me know about any side effect of LA3 that would effect my heart.
    Thank you

    1. Aurora says:

      Hi Markey! Although there are no known side effects of LA-3, I do suggest you consult your doctor about our product first to ensure that you do not experience any interactions when taking it. If you have any more questions, please feel free to reach out to me at Aurora@LiveCellResearch.com.

  6. Bobby ERVIN says:

    How can I buy the product

    1. Cheryl says:

      Go to LCR Health

  7. Jeanette says:

    I have been on LA-3 for one month. I have lost no weight. My appetite has not decreased. I do have more energy, but I attribute that to the weather being nice and that I have more things to keep me busy.

    1. Aurora says:

      Hi Jeanette! I am so sorry to hear that you are not experiencing all of the results you had expected when taking LA-3. While many of our customers have reported experiencing positive results, we do understand that it may not work for everyone. If you purchased it directly from our website, I would be more than happy to issue you a refund! You can reach me at Aurora@livecellresearch.com!

  8. Marie Andrews says:

    Day 5 of using the product I noticed an increase in my energy and a decrease in hunger. Three weeks on eating less, not so hungry anymore, have noticed my mid section is on the decrease.and NO side effects looking forward to a slimmer me for holidays in September. Yes this product works for me and its the only product that has -Thank you. I would like to order another bottle please, or if someone has some that they don’t want I will have it, unopened of course.

  9. ALMAL says:


  10. Lisa Jordan says:

    OK I cancelled after I placed order no problem at all. However I got the product anyway. I called and they said they forgot to stop the order but I can keep for free. No problems and I definitely have energy. No side affects, and yes I did get credit. Everyone is different.

  11. Wenny says:

    I’ve been using LA3 for a month and 1 week. I lost 8 lbs so far. I admit I am having a little diarrhea. Nothing major. Appetite has decreased energy levels are up. I am going to switch to 1 a day rather then 2 to see if that helps. Otherwise it works for me.

  12. Rhoda Elliott says:

    I’ve purchased product & not had any results would like to return & get refund. No information on their site. Can you help me?

    1. Alana says:

      Live Cell Research
      10866 Washington Blvd #815
      Culver City, CA 90232

    2. Aurora says:

      Hi Rhoda! I am so sorry to hear that you did not experience all of the results you had expected. If you still need assistance with a refund, please feel free to e-mail me at Aurora@livecellresearch.com!

  13. billybduck says:

    I want a refund,, I have three bottles un opened,, tried for two months.

    1. Aurora says:

      Hi Billy! I can assist you with a refund right away. Please e-mail me directly at Aurora@livecellresearch.com! I look forward to hearing from you!

  14. Gaye says:

    I would like to purchase your product Thanks

    1. Aurora says:

      Hi Gaye! You can purchase our products directly on our website, http://www.livecellresearch.com. Or I can assist you! You can e-mail me at Aurora@livecellresearch.com! I look forward to hearing from you and assisting you with your purchase!

  15. Jerrylhumphries says:

    I’ld like to purchase this product, but the price vary quite a bit. I’ld like to see if I can get it for $39.00 a bottle with return options. Where can I get this product at this price?

    1. Terri says:

      LCR website
      Conisidered but not sure after the review

    2. Aurora says:

      Hi Jerryl! Thank you for reaching out. LA-3 is available for purchase on our website, http://www.livecellresearch.com, for $46.99. I just wanted to let you know that if you decided to purchase from a 3rd party website, we cannot guarantee the product’s safety and purity. Also, we will not be able to issue you a refund if you purchased from a 3rd party website. If you have any more questions, please feel free to e-mail me at Aurora@livecellresearch.com!

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