• LCR Health Active Stem

    8 mins.
    LCR Health Active Stem is a supplement that claims to improve cognitive ability, improve muscle and joint strength, and increase longevity. The supplement is based on stem cell research that suggests that adult stem cells have a wide range of beneficial effects.

    LCR Health is a California-based company with a focus on scientific research. LCR Health is led by Dr. R.S. McClain and is dedicated to extending lifespan and health.

    LCR Health Active Stem Pros

    • Unlikely to cause side effects

    LCR Health Active Stem Cons

    • Lacks any real evidence that it will work as described
    • Expensive
    • Directions for use are not provided
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    LCR Health Active Stem

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    What You Need To Know About LCR Health Active Stem

    Active Stem is supposed to increase cognitive ability and other physical benefits and it seems to reflect current stem cell research. However, there is no proof that LCR Health Active Stem will increase adult stem cell count as promised. In fact, we can’t see any real link between this product and actual stem cell research. In addition, it is expensive and the lack of directions is of concern as is the validity of the guarantee and the lack of customer feedback.

    What Are The Side Effects Of LCR Health Active Stem?

    LCR Health Active Stem looks safe and side effects shouldn’t be an issue for most people. However, it may contain caffeine, which could lead to mild caffeine side effects. In addition, L carnosine may lower blood pressure levels. Check with your doctor first if you are taking medication in case of drug interactions.

    How Much Does LCR Health Active Stem Cost?

    LCR Health Active Stem is expensive. 1 tub (30-day supply) costs $46.99. 3 tubs (90-day supply) costs $117.00. 6 tubs (180-day supply) costs $214.27.

    US shipping is only free on orders over $50.00.

    Our Verdict On LCR Health Active Stem

    We are not impressed with LCR Health Active Stem. There is zero evidence that this powder will work in the way as advertised and increase adult stem cells as promised. This theory has never been tested on humans and, in addition, there is very little information about the so-called lab testing carried out by the company leader Dr Rand McLain.

    We have real concerns about any company that advertises a product and then fails to tell customers how to use it. Yet this is what has happened here. Added to this, there is no real customer feedback and the little available includes a customer complaint about the difficulty of obtaining the advertised money-back refund.

    We like that LCR Active Stem looks safe but in our opinion, this supplement is unlikely to do anything more than countless other health drinks on the market. It is farcical that this product claims any relation to what stem cells and research into this area of biology can do. We do not recommend LCR Health Active Stem to our readers.

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    LCR Health Active Stem Review

    LCR Health Active Stem is a general purpose health supplement in powder form that may have a nootropic effect in that it may boost cognitive ability and mental performance. In addition, it may help improve muscle and joint strength and increase longevity. Obviously, nobody will know whether this last claim is really true until it is too late, but if this supplement really works as described, you should experience noticeable benefits.

    LCR Health Active Stem Facts

    • Supplement in powder form
    • Contains five ingredients
    • No real evidence it will work in the way as described

    According to the product information, LCR Active Stem is based on stem cell research. This is not as alarming as it sounds because it has not been carried out on embryos, but instead on tissue samples from adult volunteers. Adult stem cells are cells in the body that multiply by cell division and replenish dying cells. They also regenerate damaged tissue. Adult stem cells are undifferentiated cells which means they can change from one type of cell to another wherever needed by the body so play a vital role in maintaining health and theoretically could prevent and cure diseases.

    It is important to point out here that the studies in the adult stem cells are in their infancy and according to scientists we are a long way from finding any sort of real medical cure from adult stem cells yet. However, according to the product information, laboratory testing shows that LCR Active Stem increases the proliferation of adult stem cells. We can’t help but feel that if this were the case then Dr. McClain (if he exists) would be much more involved in cutting-edge medical research than he appears to be.

    How to Take LCR Health Active Stem

    Directions are not provided.

    LCR Active Stem contains five ingredients. There is a proprietary blend comprised of L Leucine, an essential amino acid which the body needs but cannot produce, plus blueberry fruit and green leaf tea extract, both of which are high in antioxidants. It contains L Carnosine, a combination of two amino acids Alanine and Histidine. Studies have shown that L Carnosine supplements may improve neurological function and age-related conditions such as cataracts.

    The final ingredient is vitamin D as Cholecalciferol. Vitamin D is synthesised from sunlight and is extremely important for bone health, as well as numerous functions in the body.

    LCR Health Active Stem Concerns:

    • Only available from the official website. Is this company concerned about the risk of adverse feedback?
    • The guarantee looks good, but will LCR Health really honour the agreement. According to one customer’s experience, it seems unlikely

    LCR Health is based in California. According to the “about us” information, the company is headed by Dr Rand McClain, a sports medicine doctor who still operates as such in Los Angeles. He is described as a pioneer in “Rejuvenative, Regenerative (“Anti-Aging”), Cosmetic and Family Medicine.”

    LCR Health only appears to market this one supplement and despite the authoritative look of the website with its description of stem cell research, like every other supplement on the market, it is unapproved by the FDA and not intended to treat or cure any medical condition.

    What Does LCR Health Active Stem Claim To Do?

    According to the product information, there are three benefits to taking this supplement:

    • Improved Cognitive Function
    • Enhanced Joint and Muscle Strength
    • Increased Longevity

    In addition, it states that,

    each serving contains 1400 mg of five potent ingredients that have never been combined before.

    We find this statement hard to believe because we have seen numerous supplements with a very similar ingredients profile.

    The advertising briefly mentions the clinical studies into this supplement,

    …which, in clinical studies, have been shown to increase adult stem cell proliferation in vitro.

    This simply means that the cells have been tested under lab conditions. There is no evidence anywhere that proves that this supplement will have the same effects in the human body.

    Strangely, the product information does not explain how to mix this supplement or when to take it, which is a serious omission.

    Does LCR Health Active Stem Work?

    Let’s look at the facts. According to the product information, this powdered supplement harnesses the power of stem cell research, and by drinking this potion you will prevent cell damage and live longer and healthier. If this were really proven to be effective it would be the stem cell breakthrough of the century!

    There is no evidence anywhere that proves that this supplement will work as described. There are no links to any independent research that proves that the ingredients contained in LCR Active Stem will encourage the proliferation of adult stem cells.

    That said, it looks like a healthy drink without side effects.

    What Are The Ingredients of LCR Health Active Stem?

    LCR Active Stem is a powdered supplement that you add to liquid in order to make a health drink. Each serving is equal to one 3.9 g scoop of powder so there are obviously a lot of filler ingredients given that the proprietary blend adds up to just 1.4 g.

    We would have liked to have provided the results of the clinical testing carried out by Dr Rand McClain but he does not provide this information. Instead, we will look at the individual ingredients.

    • Vitamin D ( as Cholecalciferol) ( 2.000 IU): Important for bone health and the prevention of old-fashioned diseases such as rickets, vitamin D is also important for the immune system. In large doses, it can cause side effects but here in a reasonably safe serving size. Many scientists believe that we should all be taking more vitamin D because of its numerous health benefits.

    Proprietary blend (1,400mg):

    • L Leucine: This amino acid is necessary for health and can only be obtained by diet; it is present in dairy, meat and fish. It is sometimes taken for weight loss and building muscle but it lacks any real evidence because this has been mainly tested on animals.
    • Blueberry fruit: Rich in antioxidants – molecules that have a protective effect upon cells because they inhibit oxidisation, blueberries are good for health especially when consumed as natural fruit.
    • Green tea extract: We all love green tea. When added to part of your regular diet it may have real health benefits. However, there is no real evidence it will help you live longer or do anything much when taken in supplement form. Although green tea contains antioxidants called polyphenols, which are proven to prevent damage caused by free radicals, this does not seem to make much difference to lifespan or health in supplement form.
    • L Carnosine: This combination of two amino acids Alanine and Histidine is manufactured in the body, and is a substance that has an antioxidant effect which prevents free radical cell damage. This substance is been investigated as a potential treatment for Alzheimer’s disease and other mental disorders such as autism, but as yet results are not conclusive.

    Does LCR Health Active Stem Have Any Side Effects?

    Side effects are unlikely. However, green tea contains caffeine so may cause mild caffeine-related side effects such as jitteriness and insomnia. L carnosine may cause blood pressure to drop. In addition, some of the ingredients may cause interactions with medication.

    The product information does not provide any safety information.

    Not suitable for individuals under 18. Avoid if you are pregnant or breast feeding. Speak to your doctor first if you are taking prescription medication as this supplement may cause interactions.

    Are There Any Customer Reviews For LCR Health Active Stem?

    LCR Active Stem only seems to be on sale via the official LCR Health website so there is no platform for customer comments. However, we found some people discussing LCR Active Stem on the Hiya website.

    There is one positive review but fellow reviewers have lambasted this as a fake!

    It reads,

    I am an Anthropologist and take my health seriously because no one else will. We, as individuals, are responsible for our health and well-being. I researched many supplements, and Active Stem is one of the few that have an iron-clad, 90-day money back guarantee. It can’t get any better than that. The product works, hence the confidence of their products!

    We are inclined to agree with the reviewer who commented,

    That’s obviously a fake review!

    Others joined in the discussion. This customer asked the reviewer,

    What results have you experienced? How long have you taken it? What health problems do you have, or did you have? This review tells me little, except that you were able to return it and get your money back. Great! But that speaks to nothing of the product itself, or you. Provide more information, please.

    Another customer asked,

    What did the stem cell product do for you? Your comments seemed to focus more on the money back guarantee, rather than the actual effectiveness of this product. Examples of what it did would be most helpful…

    The reviewer did not reply to these questions.

    One customer comment reports trying the supplement. However, he was not as satisfied as the (fake) reviewer and had serious doubts about the supplement and the advertised guarantee.

    I tried a couple of their products for a month, with no results or being reenergized in any way. I suffer from fibromyalgia and chronic fatigue, and their products did not help me. Also, I am currently having problems returning the products for a full refund. They want to only refund me for the unused portion, which is totally not the way it was presented to me when I purchased them. I will be contacting the Better Business Bureau, and cancelling payments on my credit card.

    Does LCR Health Active Stem Offer a Money-Back Guarantee?

    LCR Active Stem does come with an advertised 90-day guarantee. Here’s what the company says about it;

    LCR Health is proud to offer a 90-Day, Ironclad Guarantee on every single order of Active Stem. If for any reason this revolutionary formula does not meet your expectations, simply send it back for a full refund of the purchase price.

    You can even use the entire supply and simply send back the empty bottles — that’s how confident we are that you’ll love this incredible health breakthrough.

    This sounds great, but according to one customer, LCR Health did not keep to this agreement.

    Where Can I Buy LCR Health Active Stem?

    LCR Active Stem is only available directly from the official LCR Health website.

    How does LCR Health Active Stem compare to Phentaslim?

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    Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

    32 comments on “LCR Health Active Stem”

    1. Frances Morey says:

      I purchased it based on “the story” to use the body’s own circulating stem cells in an attempt to eliminate joint pain in my knees. I heard about the injections of stem cells in Canada, (as the procedure is not approved for use in the US so far) and this methodology sounded logical and less invasive. I prefer not to have to resort to knee replacement surgery due to the iffy outcomes reported.
      I regret buying a six month supply and wish that I had only agreed to try it for one month to see if there was any benificial outcome. A friend suggested adding collagen to the regimen so that the stem cells would have what they need to rebuild the knee padding collagen. I became alarmed this morning when I tried to call the LCR Health customer service numbers for advice on how to use the product and both were not working numbers. I feel the sting.

    2. Kathy S says:

      Active-PK is still on the market. I purchased it weeks ago. Is there negative feedback on these capsules.

    3. Jane M says:

      Active Stem is not a weight loss supplement.

      Copied straight from their website, benefits claimed are:
      – Improved Cognitive Function
      – Enhanced Joint and Muscle Strength
      – Increased Longevity

      For what is worth, I am 52 years old, take it once a day when I need it, and it does improve cognitive function (alertness, focus and concentration span to me), helps my muscles/tendons recover from training (running, cycling and swimming), and stops niggling joint pains (knees, hips and lower spine). I don’t know about longevity, but who cares… I feel fabulous and have a great quality of life!

    4. steve chodos says:

      How do I start the refunding procedure for the six containers that i paid for and never received???

      1. stephen d chodos says:

        Thank you for the refund you sent me for your product. I appreciate your gesture. Happy Holidays

    5. Steven says:

      I find this review to be suspect. There are multiple inaccuracies in the information provided.

      I do not know if Active Stem works, but visit lcrhealth.com and you will see that Active-PK is avialable, find instructions on use, and see links to research about their ingredients.

      1. Taylor says:

        Hi Steven! I’m Taylor from LCR Health. Thank you so much for bringing this to our attention! I have sent an e-mail to the administrator of this website to have them remove this line. Because you are correct… Active-PK is still very much available! All up-to-date information can be found on our website, http://www.lcrhealth.com. Thank you for your assistance! If you ever have any more questions or comments, please feel free to e-mail me at [email protected]. Thank you!



      will not return replies regarding my complaints

      1. Taylor says:

        Hi Steve! I’m Taylor from LCR Health. Based on your most recent review, I can see that your refund was returned successfully! I am so happy to hear this. For future reference, please know that LCR Health does not run this website so we do not check it often, although we do our best to respond in a timely manner. If you ever have any issues in the future, please check our official website, http://www.lcrhealth.com for our direct contact information! You can also always e-mail me at [email protected]. Take care!

    7. steve chodos says:

      i sent in reply two days ago and have not have not heard from anyone, and my message is gone – what’s going on? the reply complained about your delivery system – is that why it was thrown away?

    8. Judy F says:

      I don’t agree with this review at all on Active Stem. I am 62 years old have arthritis in my joints, knees mostly but had spread to my left arm, shoulder, and my right hand. I also had a hard time sleeping due to a deep pain in my leg/calves but told not restless leg syndrome but kept me awake at night. I took a chance on Active stem and have used it consistently for 1 full month so far and TOTALLY IMPRESSED. After the 3 or 4th day I noticed a higher energy level and didn’t have the deep pain in my legs. After another day or so I noticed my shoulder and arm didn’t hurt and that I had improved walking. After a full week my hand was not hurting and I was back to where I could open a jar or pick something up without pain. It does taste AWFUL though and does not mix well. The container says to drink in 16 oz of water. I have found the best way for me is to use a glass jar or container put in the scoop and fill it with water comes out a little shy of the 16 oz. I use a flavored water to help the tea. Raspberry Black Tea is what I prefer. When combined don’t stir but shake, shake and shake some more. In fact, I drink a large part of it then shake it again. The last sip is the worst but as good as I feel I will drink it. I have kept a daily log of all and no side effects just some different aches in my feet and ankles as my walking is changing but exercising more and now no issue. I plan to stick with it and will order again. I contribute the pain free to high level of anti-inflammatory relief as swelling and heat in joints is down. This review seems to be an opinions and not sure author tried it but so far so good for me.

      1. Owen says:

        Ever heard of the placebo effect? Exactly how they take your money without you figuring out that they scammed you. I’ve worked with countless people at my local Senior Center that have fallen for scams like this. Don’t trust the brand, they’re just trying to sell you stuff. Ask your doctor, he’ll tell you that this “secret anti-aging formula” made of blueberry extract and all these science mumbo-jumbo is just them trying to sound smart because they have no science to back them up. There are horrible people waiting to prey on you, don’t fall for it.

        1. Taylor says:

          Hi Owen, I’m Taylor from LCR Health. Thank you so much for taking the time to leave some input. I would like to touch on some of the points you have made in your review. We are a reputable and prestigious company that takes pride in creating products that improve health on a cellular level through our cutting-edge technology and breakthroughs. We would absolutely never sell a product that we did not 100% believe in… That would be highly unethical. If you are ever interested in giving our products a try so you can leave a more accurate review, please feel free to e-mail me at [email protected]. Take care!

      2. Lisa B says:

        Hi Judy,

        Are you still experiencing good results? I’m on day 2 and I’m hoping it helps with arthritis pain and fatigue. I’m 52 and have a physically demanding job, this could be VERY helpful for me if it workds

    9. Danny C.- Dallas, TX says:

      I’ve read all of the comments posted here. Everything I’m reading here references “Active PK”. I haven’t tried that particular product. The product that I’m currently taking, which is what Watchdog is providing their review for, is Active Stem. It’s also made by LCR Health. My story: I’m an active 48 y/o male. I’ve always been in pretty decent shape, probably because I have to chase my 8 y/o daughter around so much. 🙂 I’m 5’10” and 3.5 months ago my weight had reached ~215 lbs. Besides my weight concerns, I’ve had left shoulder pain when I raise my arm over my head and my hip was insanely sore the day after doing anything greater than a brisk walk. After 3 months of Active Stem, my weight is currently at 185 lbs, my energy levels are very high and the shoulder and hip pain that I had grown accustom to has seemed to dissipate. I can’t say that my weight loss is 100% attributed to Active Stem. The increase in energy from it may have been the spark I needed to start exercising more routinely which had a greater impact on my weight. I literally feel 10-15 years younger! I also want to mention that the results I’m seeing aren’t all physical. My overall thought processing, clarity and memory are seeing improvements. I ordered another 3 month supply of the Active Stem, 2 days ago, and can’t wait to see how I’m feeling in another 3 months. Maybe my results aren’t typical? But, I pray that all of you find something that can help you feel even half as good as I’m feeling. God bless!

    10. Tom Whittington says:

      Tastes awfull. Disrupts my sleep. Gained 12 pounds in two months. NO Positive results. Contact # for refund is NO Good!

      1. Taylor says:

        Hi Tom! I’m Taylor from LCR Health. I am so sorry to hear that your experience with our product was not what you had expected. Our Customer Service team is standing by 5am to 7pm, PST Monday – Friday and 6am to 4:30pm, PST Saturday – Sunday. Our number is: 800-384-8308. If you are not able to get a hold of us there, you can e-mail me directly at [email protected] and I can assist you right away with the refund process! I look forward to hearing from you.

    11. Richard Radford says:

      I use it I love it I need a refill I can’t get to get it 816-914-6049 call me

      1. Danny C.- Dallas, TX says:

        Good morning Richard. I just ordered my 2nd 90 day supply of Active Stem. I’m 48 years old and I’m seeing major positive changes from this product. The number I called to reorder is: 844-650-5933. I’ve never tried any sort of supplement prior to this one and I’ve started recommending it to my family and friends. Take care!

    12. M. hatch says:

      I too ordered 3 bottles. It’s been a month of consistent consumption, with a cup of water on an empty stomach each morning. As I feel a bit more energetic, (could be all in my head) and I’m going up and down in my weight depending on my consumption therefore, Active PK in my book gets a thumbs down. My stomach is still the first place that the fat shows up. Yep, it’s a negative!

      1. Taylor says:

        Hi M. Hatch, I’m Taylor from LCR Health. Thank you for leaving us a review! We do suggest that you try our product for at least 90-Days to experience it’s full benefits. If you’re still not satisfied once you reach that 90-Day point, I can assist you right away with a full refund! Just e-mail me at [email protected] if that time ever comes!

    13. T. ruben says:

      I bought 3 bottles of the Active PK at a special price of 117.00, ducking the many additional offers, including Active Stem. The main ingredient is 450mg of gynostemma pantaphylum. It seems to be disrupting my sleep pattern so far. Wiki says it has another name, Jiaogulan, or “stranded blue plant”, also white mulberry, and know also as “southern ginseng”. On WebMD it mentions Jiaogulan is sometimes used as an anti-oxident. Since take no other meds., and pretty healthy, alittle overweight, I am going to take half doses, just 1 pill a day. I have a 90 day supply, so at one pill a day, I’ve got plenty to keep testing its, hopefully positive effects, to stimulate my body to more efficiently use my stored fat. We’ll see.

      1. Taylor says:

        Hi T. Ruben! Thank you for taking the time to leave such a thorough review. As with all products, I do suggest that you consult your primary physician first to ensure that you do not experience any interactions while on Active-PK. If you are still not satisfied with Active-PK, I would be more than happy to offer you a full refund if that time ever comes! Please feel free to e-mail me at [email protected] if you have any more questions or concerns. Thank you!

    14. joanne zanfardino says:


      1. Taylor says:

        Hi Joanne! Thank you for so much for reaching out. I am so sorry to hear that you did not experience the results you had expected with Active-PK… We always suggest that you try Active-PK for at least 90-Days to experience it’s full benefits. I would absolutely love to offer you a full refund just for giving our product a try though, regardless of how long it’s been. Please e-mail me at [email protected] and I can begin the refund process right away!

    15. Brenda says:

      So far I am not feeling well, I am having hot flashes and my heart has had a couple of episodes of arrhythmia. I am also having stomach issues such as nausea and diarrhea. I went on line to read side effects and found out what I ordered is no longer on the market, and now I don’t know what to do. I don’t know possible side effects???

      1. Taylor says:

        Hi Brenda! Taylor from LCR Health here. Thank you for taking the time to reach out! We always suggest that you consult your primary physician before beginning any new product, especially if you are experiencing any side effects. Please e-mail me directly at [email protected] so I can assist you further! Thank you!

    16. Rex Gass says:

      I have been in touch with LCR Health. Their replacement for Active-PK is called LA-3. It has nearly identical ingredients to Active-PK except there is 50 mg less of Gynostemma pentaphylium leaf extract in the product named LA-3. I had my pharmacist help me research the ingredients and possible interaction of Active-PK (now sold as LA-3)with my Doctor prescribed medications. It was determined that Active-PK may possibly affect the effectiveness of Coumadin (anti-coagulent most commonly called a blood thinner). I went on to have my Primary Care Physician review all the information from my Pharmacist. She recommended that I test my INR more than once per week and adjust my coumadin dosage as needed if I chose to start taking the supplement Active-PK (now sold as LA-3)

    17. anna szabolcsi says:

      no effect , absolute scam and no contact number to call

      1. readthe website says:


    18. anna szabolcsi says:

      Active Pk orderd 3 bottles . I needed to pay also tax on it . Absolutely no effect . I want to recieve my money back and try to find their email

      1. Taylor says:

        Hi Anna, I’m Taylor from LCR Health. Thank you so much for taking the time to leave us a review. I am so sorry to hear that you did not experience the results you had expected when using Active-PK. As with all products, we do understand that Active-PK may not work for everyone. I would love to offer you a full refund just for giving our product a try, regardless of how long it’s been. Please e-mail me directly at [email protected] and I can begin the refund process right away!

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