Mangodrin is a diet pill that contains African Mango extract, plus high levels of caffeine and other stimulants. We look into Mangodrin to find out if it is worth the risk of stimulant side effects or whether is just another diet pill that will leave you feeling wired, anxious and still overweight.

There has been a lot of hype around African mango as a weight loss aid and many supplements have come onto the market in an attempt to cash in on its name. Although African mango seems safe, some of the ingredients contained in Mangodrin are a matter of concern. This supplement contains a lot of stimulants which will not suit everyone and African mango itself may not work in the miracle way as advertised.

Mangodrin Pros

  • Some positive customer feedback
  • Available to buy in shops as well as online
  • May help achieve modest weight loss

Mangodrin Cons

  • Some ingredients potentially dangerous
  • Inadequate product guarantee
  • Inadequate product information in plain English
Watchdog Rejected Diet Pills

Mangodrin Review

Mangodrin Facts

  • Made by American company TruDerma
  • 60 capsules in each pack
  • Contains patented African mango supplement IGOB131.

Mangodrin is a best selling American diet pill made by TruDerma LLC. They make two products under the Mangodrin name – this one, the original Mangodrin sometimes called Mangodrin Xtreme and there is also a stimulant free version called Mangodrin SF. According to TruDerma, Mangodrin Xtreme will give you enhanced energy and focus, suppress your appetite and may also help you lose weight.

The supplements both contain patented African Mango seed extract and advertise the patent number, which is IGOB131.

This diet pill is in capsule form. You are advised to take one capsule twice daily, 60-90 minutes before meals. There is not much information given by the company regarding your diet and lifestyle throughout taking the pills but judging by the stimulant content we advise that you do not take Mangodrin Xtreme too close to bedtime. The company suggest you buy Mangodrin SF to take overnight.

African mango or Irvingia Gabonensis to give it its botanical name (read our in-depth Irvingia Gabonensis article here), is the principle ingredient and clinical testing carried out in Cameroon has shown that it can help weight loss. Mangodrin contains patented African Mango Seed extract IGOB131 and is exactly the same material as used in the clinical test. All participants taking part in the 10 week clinical trial showed improvements to waist, circumference, body fat, weight and cholesterol levels.

However, before we all get too carried away, rush out, and buy it, this clinical testing was only carried out on 102 people. Although this may prove that in this University of Yaoundé test, the participants all received positive benefits, further testing is necessary to ascertain if this effect will be as good on a larger scale or under different test conditions.

As well as the African Mango, Mangodrin contains high levels of caffeine and other stimulant ingredients.

Despite the links to clinical evidence surrounding the active ingredient, the Mangodrin website does not offer much in the way of information beyond the usual stock before and after photos and a graph that looks scientific but does not provide any real facts. The company offer a free slimming recipe eBook with every order.

Mangodrin Concerns

  • Some of the ingredients may be dangerous to health
  • Company do not appear to honour the guarantee
  • Somewhat relies on evidence supporting African Mango Seed extract for weight loss

What Does Mangodrin Claim To Do?

According to the advertising, Mangodrin offers the following weight loss benefits.

  • Improves fat burning by aiding insulin sensitivity with the up regulation of adiponectin expression
  • Improving the dual weight control of leptin by lowering levels of C reactive protein
  • Reducing the amount of glucose in the body that converts to fat by inhibiting the enzyme glycerol 3 phosphate dehygronase
  • Reducing the amounts of starch absorbed as glucose by inhibiting the amaylse enzyme
  • Combining the effects of losing pounds with improving cholesterol levels to promote youthful skin at a cellular level.

This all sounds very scientific but confusing. Does anyone really know about the “up regulation of adiponectin expression” and what this means? We feel that these scientific statements are there to create a serious impression, rather than pass on any information and the lack of dosage information and possible effects that this supplement may cause would have been more useful to the consumer,

An easier statement is “This formula is for SERIOUS DIETERS only and should not be taken by those that are sensitive to stimulants or only looking to shed a few “vanity” pounds” but they do not go onto explain why.

A strange part of the Mangodrin advertising is that they save most of the information for use on the Mangodrin box. According to this, you can expect to lose 28lbs within 10 weeks. This sounds a lot but in fact, losing 2.8 lbs a week is a reasonable enough claim.

So What Is Mangodrin and What Are The Ingredients For Mangodrin?

Mangodrin is a diet pill that contains African mango seeds extract combined with some stimulant ingredients. It is supposed to work by reducing your appetite, increasing your energy and delivering the weight loss effects of African mango. It may help you achieve a slight weight loss, depending on your own efforts, but it does come with a few side effects.

Contents contain

  • Caffeine (200mg): Caffeine can help suppress the appetite and increase the metabolism. 200mg is around the same serving as an average two cups of instant coffee.
  • African mango seed extract IGOB131 (150mg): When the clinical testing was carried out by the University of Yaoundé in Cameroon, the test group took 150mg of seed extract twice a day which is the same as serving as found in this supplement.
    After 10 weeks, leptin levels (the hormone that causes your appetite) were shown to be reduced and there was a positive effect upon the “expression of adiponectin, a protein that helps regulate glucose (blood sugar levels) which is involved in the management of insulin. This substance may have a role in the prevention of type 2 diabetes.
  • Green tea extract (100mg): Green tea contains Catechin a type of antioxidant beneficial to health and believed to play a role in the prevention of disease .Catechins have a small positive effect upon weight loss and weight management. Green tea contains caffeine.
  • Phenethelymine HCI (26mg): This organic compound, linked to amphetamines has a short-lived effect of around 10 -15 minutes and like amphetamines release dopamine and norepinephrine chemicals in the brain that are associated with feelings of pleasure. No benefit for weight loss and potentially unsafe. Source:
  • Inositol Niacinate (25mg): Chemical compound often used in skin care supplements. Does not appear to play a role in weight loss. Source:
  • Synephrine Caprylate (20mg): This synthetic compound was first noticed in natural form in bitter orange peel and it can increase the speed of the heart and raise blood pressure, in common with other stimulants. According to the weight loss industry it is an appetite suppressant but medical research has not proved this and suggests that further testing is necessary due to concerns about safety. Source:
  • Nettle leaf extract (20mg): This commonplace plant is said to have many health benefits including potential use in the treatment of arthritis and is a source of antioxidants. Source:
  • Gluconolactone (10mg): This chemical compound is an ingredient found energy drink Red Bull. It is supposed to give a high-energy effect but there are no further details relating to dosage and safe levels. Once believed to cause brain tumours, this rumour has now been discredited. No relevance to weight loss. May have a slight effect upon mood. Source:
  • Picamilion (5mg): Supplement also known as nicotinoyl sometimes used in Russia to treat depression or glaucoma. No relevance to weight loss or appetite suppression.
  • Yohimbe extract (3mg) Has been marketed as an aphrodisiac and body builder supplement and believed to play a role in fat reduction. It can be dangerous and lead to acute neurotoxity, causing a rise in heart rate and blood pressure combined with vomiting and nausea. Source:

So What Does All This Mean?

African Mango Extract has only undergone limited clinical testing and although the results appear to be positive, this ingredient requires further proof that it works. Caffeine is the principle ingredient of Mangodrin. Some of the stimulant effects will include elevation of heart rate and blood pressure and we feel that this supplement will make you feel “too wired to eat”.

If African mango really worked as well as suggested, there would be no need for all these added ingredients and with a modest weight loss of 2.8lbs a week, it hardly seems worth the risk.

Does Mangodrin Have Any Side Effects?

Common side effects according to customers include;

  • Headaches
  • Vomiting
  • Elevated heart rate
  • Increased blood pressure
  • Jitteriness
  • Shakiness
  • Sweating

The company does not offer advice about side effects, beyond a warning to avoid if you are sensitive to stimulants. There is also a small warning printed on the packet advising you to avoid drinking caffeine.

Customer complaints include;

the side effects for me were far too much to continue using. I got hot (thermal) and shaky. I had so much pent up energy that I had to leave my office to do laps around the building twenty times before I was calm enough to sit at my desk. It made my heart beat irregular too. The day I stopped using it, I was fine…

I tried this product but it made me very sick to my stomach and I could not keep it down

I tried Mangodrin for 2 months (2 bottles) and I only lost the money I paid for the product. I did not lose a single pound over a two-month period. During this period, my heart rate and blood sugar were extremely high. I could not sleep some nights because of the high heart rate. I was nervous/jittery almost daily. I had to go to the bathroom almost every hour because the product made my bladder nervous, etc.

Caution: Avoid if you are sensitive to stimulants or suffer from a heart condition or high blood pressure. Not suitable if you are pregnant or breast feeding.

Any Mangodrin Reviews From Customers?

Yes, there is plenty of customer feedback about this diet pill and it is fairly mixed. Many customers have reported that it doesn’t work.

I tried it for a for 30 days and it I didn’t lose a single pound or inch.

I do not recommend TruDerma Mangodrin to anyone wishing to lose any weight

A couple of typical negative comments.

A large proportion of customers suffered from side effects but some Mangodrin reviews were positive

I can see the results already, specially in my stomach. I wish I can buy this product for less money. Good product for weight loss

This stuff worked pretty well. My wife and I both felt that it was a fair appetite suppressant and added a bit of energy. Not a magic bullet, but def helps with trying to eat less and maintain a healthy diet

So Does Mangodrin Work?

It might work to help you lose some weight but nobody has reported losses anywhere near 28lbs in 10 weeks, although one customer lost 10lbs in 2 months.

The main problem is that although African mango sounds good it has not been adequately tested to prove that it really works. An added issue with Mangodrin is that the stimulants can be a problem and many people experience side effects.

Most of the weight loss is reported by people already on a fairly extreme eating plan so it is highly possible that they would have lost the same weight without the pills.

Many of the ingredients contained in Mangodrin are unrelated to weight loss and there is no benefit to taking them.

Where Can I Buy Mangodrin?

You can buy Mangodrin direct from the TruDerma website. One 60 capsule pack costs $34.99 and you can make savings on larger orders. Buy three packs of Mangodrin and you get two free packs for a total of $104.97. Shipping is free to US addresses and you also get a free gift of an eBook with all orders. International shipping costs extra (not specified) and takes between 14 and 21 days.

US customers can also buy in Walgreens or from Amazon. Price is slightly cheaper from Amazon and costs around $27.49 per bottle.

What About Money Back Guarantee?

No money back guarantee is advertised but you can return unused products to the company within 30 days for a full refund. You will have to contact the company for a Return Merchandize Authorization (RMA) number.

According to one customer, this is not easy. She says;

I tried to return the product and I was told that it could take a couple of weeks to get use to it, but I never did. I called to ask for a RMA/refund and I was given a telephone number and email address that nobody ever answered

Watchdog Verdict

Mangodrin may work to help you achieve modest weight loss but many customers have had a less than positive experience with side effects. We feel that this supplement is not really worth the risk or the money it costs considering the choice available on the market.

We therefore have rejected Mangodrin diet pills.

Watchdog Rejected Diet Pills

#1 Consumer Choice 2021: Phentaslim

Phentaslim is Diet Pills Watchdog Approved


Thousands of customers have cut the fat with this fast and powerful thermogenic fat burner. Can suppress appetite, boost energy levels and elevate mood without the jitters.

  • Over 100,000 satisfied customers
  • Manufactured in a GMP facility
  • 60-day money-back guarantee
  • FREE shipping and buy 3 get 1 FREE offers!
See our Full Review here

Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

Have Your Say

7 comments on 'Mangodrin'

  1. Let me also add that I use Mangodrin SF, and I have only experienced one side affect – headaches – and those are rare.

  2. Unlike all others who use Mangodrin as a weight loss supplement, I use it for two very different reasons. Since using this product, I have seen a marked difference in my cholesterol levels (lowered bad cholesterol,increased good cholesterol and leveled triglycerides). In addition to helping with cholesterol, it helps me with acid reflux and regurgitation. I have been taking it for two years now and each time I have the same result. No, I haven’t lost much weight on this product, but the other health benefits are worth every penny.

  3. I have been using MangoDrin for a few weeks, it is great. It does help with weight loss. It does give me a small amount of energy. It has not caused any side effects AT ALL FOR ME. Just like everything else that works — it killed someone. WHICH I DO NOT BELIEVE. I noticed Jillian Michaels product has taken MangoDrin place. GO FIGURE. Sorry Jillian — I WILL NOT BUY YOUR PRODUCT!!!!!

  4. Hi. I have been using mangodrin extreme for 3 weeks and it seems to work on my belly fat. I feel the fats are dissolving in my belly area as well as the love handles. People are telling me that I have lost weight. However, on a downside it accelerates my heart rate a lot and I feel too weirs to want to eat anything.
    needs more research.

  5. Hi, there – do you plan to do a review for Mangodrin SF? I’ve been using it without any negative side effects…I tried Phentaslim based on your recommendation, and it gave me stomach pains, which I never had with Mangodrin SF, so I stopped the Phentaslim and the pain went away.

    Thank you very much, in advance, for your response.


    1. Hi Aliza,
      Thank you for your feedback. We have added Mangodrin SF to our list of supplements to review and can hopefully get this up for you soon. Please let us know how you get on with the original Mangodrin though.
      Diet Pills Watchdog Team

Add your comment

We'd love to get your opinion. Please keep it clean and stay on topic, no spamming. Comments are moderated before being made live. Your email address will not be published.
We cannot give advice about medical conditions or prescription drugs. Please direct specific medical questions to your doctor.

This site uses Akismet to reduce spam. Learn how your comment data is processed.