Nexgen Xentrafen

Nexgen Xentrafen is a maximum strength diet pill that offers maximum energy and appetite suppression. It seems popular because with over 850 positive reviews on Amazon this supplement looks like the real deal but beware, things are not always as they seem.

We take a look at Xentrafen to get to the truth about this supplement.

Xentrafen Pros

  • We cannot think of one good reason for taking this supplement

Xentrafen Cons

  • Contains dangerous ingredients
  • Insufficient ingredients information
  • Customer feedback has been manipulated
Watchdog Rejected Diet Pills

Xentrafen Review

Xentrafen Facts

  • Made by Nexgen Labs
  • Contain 60 capsules a bottle (20-30 days supply)
  • Contains synephrine, Hordenine and yohimbine – stimulants that raise adrenaline levels

Xentrafen is a diet pill that the makers Nexgen Biolabs describe as unlike any diet pill the world has ever seen… describing it as the most sophisticated weight loss product anywhere!

This type of overblown advertising claim may be corny but it does seem effective, especially if you read all the great feedback left by Xentrafen customers on Amazon. After all, we all take product reviews and customer recommendations seriously because they seem trustworthy and genuine.

That said, we cannot really understand why this diet pill is so special because the contents of this diet pill do not seem quite as spectacular as the claims.

First off, the formula is under a proprietary blend meaning you cannot see a full ingredients breakdown. This is a common fault with some diet pills because it enables the true contents to be masked and in many cases hides an inferior product. We covered proprietary fat burning blends before in a previous investigation.

However, the ingredients in Xentrafen are named and the sum total of the combined ingredients is provided. Xentrafen contains 377mg active ingredients per serving.

Xentrafen contains 1,3,7 Trimethylxanthine – more commonly known as caffeine. Sometimes diet pill companies call caffeine by this long scientific name in order to make it sound more impressive. Xentrafen contains Yohimbine, Synephrine and Hordenine – three stimulants that raise adrenaline levels as well as heart rate and blood pressure. These stimulants come with numerous health risks but increasing adrenaline levels often leads to suppressed appetite and increase energy.

Xentrafen also contains Schizandrol – plant extract known for causing a short-lived high and 5 Hydroxytryptophan an amino acid believed to raise serotonin levels. Without an ingredients breakdown it is possible that the main ingredient is simply the cheapest ingredient and in this case, it may just be caffeine.

How to Take Xentrafen

Take one capsule before lunch and another capsule before dinner.

Advanced users can take a third capsule if needed for additional appetite suppression.

Xentrafen is made by Nexgen Biolabs, a supplements company based in the United States. We have covered Nexgen supplements before and have found that all of their products have a very similar ingredients profile and style. Always high in stimulants and accompanied by misleading claims about miraculous weight loss and energy, we have yet to approve any Nexgen supplements.

Other Nexgen products include a so called Phentermine substitute called Phen Rx
and very similar in ingredients profile to Xentrafen.

We also covered JetRush – an energy pill for hardcore speed freaks! We found that as well as being potentially dangerous the claims were exaggerated and all most people got were headaches.

Nexgen have been in the National news. The company was the subject of a report by ABC news after company reps were criticized for handing out free samples of dangerous pills believed to increase mental focus, to university students on US campuses.

Xentrafen Concerns:

  • This supplement has caused some people to be hospitalized
  • The ingredients list. How much of these ingredients are actually contained in this supplement?
  • If Xentrafen really worked for weight loss, there would be no need to post hundreds of fake positive review

What Does Xentrafen Claim To Do?

According to the Xentrafen advertising, you can expect the following results:

  • Extreme weight loss
  • Maximum strength appetite suppression
  • Energy enhancement & mental focus
  • Significantly reduce BMI (body mass index)
  • Targets fat and lipid metabolism on stubborn problem areas
  • Enhance metabolic function and fat burning

Nexgen claim that:

Every component of this formula was carefully developed utilizing the absolute highest standards & the most cutting-edge ingredients available anywhere in the world, resulting in powerful weight loss quickly and easily!

In truth, there is nothing special about Xentrafen. This diet pill looks very similar to the other supplements in the Nexgen product range. It comes with no explanation about how weight loss is achieved or whether the ingredients or the formula have ever been clinically tested.

So What Is Xentrafen and What Are The Ingredients?

Xentrafen is described as a fat burner, energy enhancer and appetite suppressant. The ingredients come under a proprietary blend so we cannot provide an ingredient breakdown with quantities. The active ingredients add up to 377mg per capsule serving.

  • 1,3,7 Trimethylxanthine: This impressive scientific name is nothing other than good old caffeine. This stimulant is effective for promoting energy and does have a metabolism increasing effect. The downside is that once your body becomes accustomed to it, the effects can wear off. In addition, caffeine is known for causing side effects. The amount contained here is unknown but the average cup of coffee contains around 100mg.
  • Synephrine: Also known as bitter orange extract or Citrus Aurantium, this stimulant raises the heart rate and increases blood pressure. It is billed as a way to increase the metabolism in place of banned substance ephedrine. Synephrine is not safe and can cause heart palpitations and a whole range of side effects. It has been linked to causing heart attacks and strokes. Amount in this supplement unknown.
  • NN Dimethyltryamine: This compound more commonly called Hordenine is found in barley, flowers and synephrine. It is classified as an indirectly acting adrenergic agent that produces its pharmacological effects by releasing stored norepinephrine. This means it increases adrenaline levels and the flight or fight response. This effect may help you lose your appetite by making you feel too stressed to eat.
  • Schizandrol: This ingredient is also present in other NexGen products PhenRx and JetRush. Schizandrol is a Chinese plant extract with a stimulant effect within a few minutes of taking. The short term high will last around an hour and the side effects have not been fully investigated. It is probably unsafe. Does not appear to have an application for weight loss.
  • 5 Hydroxytryptophan: Also called 5 HTP this chemical increases serotonin levels in the brain. Serotonin is the brain chemical that affects mood, appetite, and sexual behaviour and when levels are low it can lead to depression, comfort eating and low mood. 5 HTP is produced synthetically in order to treat these issues. There is not much evidence to prove all the claims about 5HTP but trials have found that doses of 50-3000 mg daily for 2-4 weeks can improve symptoms of depression. Amounts contained in this supplement are unknown.
  • Yohimbine: Chemical derived from a tree in Africa called the Yohimbe. Yohimbine increases blood flow and is a stimulant with aphrodisiac effects making it popular in treatments for erectile dysfunction. However this ingredient is unsafe and is on the “dirty dozen” dangerous ingredients list. Side effects include changes to blood pressure, increases in heart rate and even heart attack and seizure. Here in unknown quantities and potentially dangerous.

So What Does All This Mean?

The ingredient list looks alarming. All these stimulant ingredients are known for causing side effects and in high amounts, any of these would be dangerous. When combined together, effects could be unpredictable.

The major drawback to proprietary blends like this is that it is impossible to know the exact ingredients amounts.There is only 377mg active ingredients per capsule. It is highly possible that 300mg of this is caffeine – the equivalent of 3 cups of coffee.

However, we do not know this for sure and many customers have reported side effects that are not necessarily caused by an overdose of caffeine. Nobody has mentioned a “high” effect.

Does Xentrafen Have Any Side Effects?

According to customer reviews, a very high percentage of people have experienced similar side effects relating to nausea and extreme stomach pain.

One customer related,

Have taken the pills for 2 days now, the first day the stomach pain was unbearable. If hunger suppression means you won’t eat because of the pain then these are amazing…

Many others said the same thing,

This one is HORRIBLE I feel so sick with stomach cramps.

Made me sick to my stomach. Awful taste in my mouth.

Some customers have reported jitteriness and insomnia as well,

Horrible!! Kept me up all night with a horrible jittery feeling and did NOT suppress my appetite at all. Gave me a horrible headache.

Many others have reported the same effects. Potential side effects include:

  • Stomach pains
  • Nausea
  • Cramps
  • Vomiting
  • Dizziness
  • Anxiety
  • Mood swings
  • Irregular heart beat
  • Rapid heart beat
  • Irritability
  • Headache
  • Frequent urination
  • Bloating
  • Skin rash
  • High blood pressure
  • Insomnia
  • Allergic reaction
  • Increased risk of seizure
  • Increased risk of heart attack or stroke


Avoid if you are pregnant or breast feeding.

Do not take this supplement if you have an underlying health condition especially relating to heart or blood pressure.

Avoid if you have or have had mental health issues or problems around addiction.

Do not take if you have glaucoma or are taking prescription medication.

The ingredients in this supplement come with a wide range of side effects and interactions and we are unable to cover them all.

If you suffer an allergic reaction such as chest pains, shortness of breath or skin irritation seek medical advice urgently and don’t forget to take your bottle of Xentrafen with you.

Any Xentrafen Reviews From Customers?

There are hundreds of positive reviews for Xentrafen and at first glance, this looks great. It suggests that this supplement works and with comments such as,

I stumbled upon these pills one day and saw all of the great reviews so I decided to give them a try. They are beyond amazing. I’m extremely happy that I found these pills, I am just that much closer to my goal of being a slimmer, healthier me.

However, a look at the less than positive reviews tells a different story. There are many reported side effects. This customer had an extreme reaction.

Do NOT waste your money on something that will make you sick to your stomach. After taking just one of these I spent the night in the HOSPITAL!! It was the worst thing I’ve ever experienced. Horrible side effects.

There seems to be something going on with the positive feedback reviews and a number of customers have voiced their concerns.

One customer reported,

I would give zero star if I could! Pay attention to the dates of other reviews! All on dec 11, 12th and Nov. 26th! Hmmmm may I say these interviews are all bunch of BS and done by the manufacturer.

Another customer went into more details,

Buyers beware!! All the super high reviews made me a bit skeptical, so I started clicking on the “see all my reviews” links. Guess what? All these reviewers seem to be reviewing the same products. Things like: muscle roller sticks, micro USB cables, iphone cases by luuv it, neck traction devices …

We looked into both these points and found these customers were correct. Many people are extremely angry at being manipulated with fake feedback.

As one customer asked,

Why are there so many fake reviews on these products…? Anyone with a brain can click thru and see that the reviews posted on other products by 98 % of these are also reviewing LipoX or other supplements. (FAKE FAKE and MORE FAKE) it’s such a shame as you can’t really trust if others genuinely like this product. I would have totally tried it even if there were just 5 good reviews (and no others) from actual people telling their experience. I hope Amazon eventually restricts this kind of false advertising…

So Does Xentrafen Work?

Xentrafen will not work in the way as described. Yes, it may suppress your appetite but as many customers have reported, it does this by making you too sick to eat.

The enhanced energy claims are equally inflated. Many customers have reported feelings of anxiety and jitteriness – a usual side effect of elevated adrenaline levels and too unpleasant for most people to continue with.

Some customers have wound up in hospital so it is fair to say this supplement can cause dangerous side effects.

This is not surprising. Most of the ingredients are well known as being dangerous and we do not know amount quantities either. Results and effects are going to be unpredictable, as many people have found.

A supplement that relies on fake reviews is a matter for concern too. With hundreds of fake reviews posted on the Xentrafen product page, the product advertising is extremely suspect and we would like to see Amazon deal with this issue.

If this supplement really worked, it would not need fake positive reviews.

Where Can I Buy Xentrafen?

If you are mad enough to want to try this supplement, you can buy direct from the Nexgen website. One bottle of 60 capsules (between 20 and 30 days supply) costs $44.99. Shipping costs are calculated at the point of sale.

You can also buy Xentrafen from Amazon. One bottle of 60 capsules (between 20 and 30 days supply) costs $39.99 and includes free shipping to US addresses.

Xentrafen is not available direct to customers outside the USA. If you contact Nexgen, they may ship overseas but this information is not provided by the website.

What About A Guarantee

No money back guarantee on offer.

Watchdog Verdict

There is nothing good about Xentrafen. We can find no redeeming features about this supplement. It comes from Nexgen – a company who are known for peddling substandard supplements, it contains dangerous stimulant ingredients in unknown quantities and the customer feedback has been manipulated.

In addition, many people have experienced unpleasant side effects with some people winding up in hospital as a result of taking. This is not surprising. The listed ingredients are well known for causing dangerous effects so it is likely that most people will experience problems in lesser or greater degrees. This supplement just does not look safe. It is an easy decision. We reject Xentrafen.

Watchdog Rejected Diet Pills
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1.1 out of 5
Nexgen Xentrafen
  • Effectiveness
  • Safety
  • Price / Guarantee

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Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

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