Whilst many fat burners seem to have similar ingredients that feature time and again, there are other diet pills that feature more uncommon ingredients. Norcodrene does contain some common ingredients such as caffeine and yohimbe, but also features a range of ingredients not commonly found in many diet pills.

Below we take an in-depth look to see if Norcodrene from PEScience is an effective weight loss aid.

Norcodrene Pros

  • Money-back guarantee
  • Positive customer reviews

Norcodrene Cons

  • Limited clinical studies in humans
  • No ingredients quantities provided
  • Expensive when ordered from manufacturer
Watchdog Rejected Diet Pills

Norcodrene Review

Norcodrene Facts

  • Manufactured by PEScience
  • 90 capsules per bottle (30 day supply)
  • Fat burning diet pill

Norcodrene is manufactured by PEScience, who are also known as Physique Enhancing Science. An American company, they offer a variety of products aimed at athletes and those who want to improve their physique. The company can be contacted using the contact details provided on their official website.

How to Take Norcodrene

To assess tolerance, take (1) capsule on an empty stomach 30-45 minutes before breakfast and an additional (1) capsule 5-6 hours later.

Once tolerance has been assessed, an additional (1) capsule may be added to the morning serving.

Under no circumstances should the initial serving be exceeded or the warnings on this bottle be ignored. Do not exceed 3 capsules in any 24 hour period. Do not use product for longer than 8 weeks followed by a subsequent 4 week break.

Norcodrene Concerns:

  • Limited clinical studies in humans
  • No ingredients quantities provided
  • Expensive when ordered from manufacturer

What Does Norcodrene Claim To Do?

The manufacturers of Norcodrene state that the product has the following attributes:

  • Breakthrough thermogenic
  • Energy & mood
  • Emerging science
  • Amazing feel

The company also state:

Norcodrene delivers an all new feel, focused around energy, mood, and thermogensis. With only 100 mg caffeine per capsule, the feel Norcodrene delivers will have you soon realize it stands apart from everything else in this category. The formula is a carefully formulated blend of ingredients that truly delivers.

So What Is Norcodrene and What Are The Ingredients?

The ingredients for Norcodrene are listed below. The individual ingredient quantities used are not provided because the product contains a proprietary formula. This makes it more difficult to establish the strength of the product.

Each capsule contains 225mg of the proprietary blend, and 100 mg of caffeine.

TGR5a-Infused Matrix

  • CirsiumPlex™ Blend (Cirsium Oligophyllum (whole plant) Extract): One study has shown that this plant increases lipolysis in rats, and led to significant weight loss. However, the information available about this plant is still preliminary, and it may not have the same effects in humans.
  • Japanese Thistle (root) Extract): Contains cirsimarin, which is thought to stimulate lipolysis in the body; appears to work in a similar way to caffeine, although is much stronger.
  • Grapefruit (seed) Extract (Nomilean™): May Contain Naringin, which is known to extend the amount of time that caffeine remains in the body. This would make the effects of caffeine also last longer. Research also suggests that Naringin enhances lipid (fat) metabolism in the body, which again could have positive implications for dieters.
  • Selaginella Tamariscina (whole plant) Extract (Standardized for Amentoflavone): A Chinese traditional medicine- very little available research, which seems to focus on anti-cancer properties. One study states that Amentoflavone has shown antiviral, antioxidant, antidepressant, anti-inflammatory and analgesic activity.

Thermo Energy Matrix

So What Does All This Mean?

There are numerous ingredients used in Norcodrene that are still uncommon in diet pills, but have a small amount of clinical support to suggest that they will aid weight loss. These include Selaginella Tamariscina and its active compound Amentoflavone, as well as Cirsium Oligophyllum and Japanese Thistle.

Some of these studies are in rats, and so the ingredients may not work in humans in exactly the same way. However, with these promising initial results, it would be worth keeping an eye on emerging research in the future, as these could be confirmed as good ingredients for weight loss.

Caffeine is well regarded as a mild stimulant that boosts the metabolism, increases alertness and boosts energy levels. Yohimbe has mixed results from clinical trials, but also has a long list of potential side effects.

Caution with this product is advised, and only people who are completely healthy should consider taking this product– see the list of side effects and cautions below for more details.

Does Norcodrene Have Any Side Effects?

Because there are limited studies into many of the ingredients, it is possible that not all of the possible side effects of these ingredients are documented- for example, Higenamine is largely under-researched, and could have side effects typically associated with stimulants such as increased heart rate, heart palpitations and increased sweating, although none of these have been confirmed.

There are also not many known side effects for Cirsium Oligophyllum, Japanese Thistle and Selaginella Tamariscina; we would recommend that consumers who have been sensitive to stimulants in the past, or who have heart related health problems including high blood pressure, do not consume this product, as the risks are essentially unknown. Anyone experiencing side effects should also stop consuming the product immediately.

Caffeine can cause headaches, increased blood pressure, increased heart rate, heart palpitations, increased urination, jitteriness, dehydration and insomnia.

Yohimbe can cause a wide range of side effects, including stomach upset, excitation, tremor, sleep problems, anxiety or agitation, high blood pressure, a racing heartbeat, dizziness, stomach problems, drooling, sinus pain, irritability, headache, frequent urination, bloating, rash, nausea, and vomiting. High doses can cause more severe effects.

Do not use in combination with caffeine or any stimulants from other sources including but not limited to coffee, tea, soda, and other dietary supplements or medications.

Do not combine with alcohol.

Do not use under extreme conditions of heat, sleep deprivation, or dehydration.

This product is only intended to be consumed by healthy adults 18 years of age or older.

Consult with your physician before using this product, especially if you are using any prescription or over the counter medication or if you have pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney, or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication.

Do not take this product if you are pregnant or nursing.

Discontinue use 2 weeks prior to surgery.

Discontinue use and consult your health care professional if you experience an adverse reaction to this product.

Do not exceed recommended serving.

Do not use if safety seal is broken or missing.


Any Norcodrene Reviews From Customers?

As the product is sold on, there are numerous customer reviews that have been left for Norcodrene. The majority of these are incredibly positive.

Wow! I received a few free samples of the Norcodrene and Alphamine from a woman working at the Vitamin Shoppe when I went to replenish my usual stock. I had just ordered a bottle of True Grit by Thermo that I was very happy with. I decided to try the Norcodrene anyways and I’m so glad I did. It helps to wake me in the morning and focus while I’m at work. I don’t even notice the time going by until people start leaving for lunch. This suppresses my appetite for a solid six+ hours. I didn’t experience an intense thermo feeling, but it was light enough for me to notice I had taken it. Also, if possible, I felt somewhat relaxed while taking this. Aaaah, what a feeling. Oh, and the main purpose: I love working out but this just makes the time fly by. I recommend to anyone.

Best thermogenic I have ever purchased. Very strong appetite suppressant, clean energy, and great mood enhancer. I would honestly just buy it for the mood enhancement. Should give it a try and very good price. I wish I learned about this product earlier. Warning: should not take I’d you are sensitive to yohimbine.

I love this product. I’m a stim junkie, i need a pick me up in the morning. I’ve tried alot of different fat burners and this by far is the best. Its gentle on the stomach, a good boost of energy without crazy jitters, cold sweats etc. This is also the first time i have experienced appetite suppression from a fat burner. I’ve been consistent with diet and exercise losing about 1lb a week but once i started taking this, i lost 2lbs in a week. Two pills on an empty stomach works for me. overall, I’m very happy with this product, its a must try!

Worth buying for the mood enhancement alone. Hesitate to even classify this as a fat burner as it really has nothing in common with any other on the market. The energy is clean and sustained – high quality yohimbe and caffeine that never gives you even a hint of jitters. On my 2nd bottle now and would recommend this to almost anyone regardless of goals – easy to add for simple mood enhancement / in place of caffeine in a stack. I prefer this to Alphamine for a stand alone supplement – latter is better for PWO or in the afternoon for an energy jolt. One of my favorite products from PES.

There are also numerous customer reviews on amazon. Whilst the majority are positive there are also a few low-rated negative reviews of Norcodrene.

It doesn’t curb appetite, it doesnt help with energy, it doesnt seem to do much of anything. It also doesnt seem very uniform from dose to dose. Some days it can make you jittery like youve had too much coffee, and some days you can take a nap after you take them. Taking them before exercise they dont seem to bring anything to the party.

It gives me some energy. Havent noticed a difference in appetite. Havent noticed a difference in weight decrease although I do watch what I eat. Have been taking it for over 2 months.

So Does Norcodrene Work?

The customer reviews certainly suggest that the majority of customers are impressed with the product, and lose some weight whilst using it. However, the product is not suitable for all consumers- the company have provided a comprehensive list of who can and cannot use Norcodrene, which is provided above in the side effects section.

The ingredients list is a mix of some commonly used diet pill ingredients, and some more unusual ones. Yohimbe carries the risk of a variety of unpleasant side effects, but clinical studies are divided about its effectiveness in aiding weight loss.

Caffeine is known to be a mild metabolism boosting ingredient, but its effects are still relatively small. At the maximum daily dosage, consumers will be taking 300 mg of caffeine per day; they should limit their intake of caffeine from other sources including beverages, to minimise the chances of side effects occurring.

The other ingredients used in this product are far more uncommon, but appear to have completely positive, although very limited clinical studies associated with them. At this time, there is not enough evidence to prove the safety and lack of side effects of these ingredients, and many of the clinical trials have been performed in rats, making them preliminary at best.

Where Can I Buy Norcodrene?

Norcodrene is available from numerous online retailers, including from the manufacturer’s official website.

From Amazon, a single bottle of Norcodrene is available for $29.99 plus shipping. Shipping is offered for free when the order total is $35 or more, such as when a customer orders two or more bottles at once.

From, a single bottle of 90 capsules costs $37.48 plus delivery. GNC offer the product for $32.99 plus delivery, or those with a GNC membership can get a discounted price of $29.99 per bottle.

From the PE Science website (the manufacturer’s website), the product costs $49.99 for a single bottle. We obviously recommend shopping around for this product, rather than purchasing the product at such a high price.

What About A Guarantee

PEScience now offer a money-back guarantee on the products purchased directly from their website. They state:

At PEScience we offer a 100% money back guarantee for all of our products. If you did not like the taste of a specific product or it did not suit you well, email [email protected] and we will gladly take care of you.

Returns policies may vary between other retailers. have a comprehensive returns policy that covers opened and unopened products.

Watchdog Verdict

Norcodrene is an interesting diet pill that contains many relatively unknown ingredients. Whilst these have some basic clinical support to suggest that they do increase fat burning in the body, there is still a lack of detailed research, especially in humans. This means that the actual effects, and side effects of some of the ingredients are not completely known, making this diet pill a step in the dark.

Consumers may lose weight, as evidenced by many of the customer reviews, but they may also experience unpleasant side effects.

We suggest that consumers who have any of the health problems listed in the side effects section avoid this product completely. Other consumers may still want to try the product, but weight loss is not guaranteed. The product is covered by a money-back guarantee when ordered from the manufacturer, which does not seem to have a time constraint, which is helpful for those unsure about the product.

The customer reviews in general are very positive, with only a small number that did not lose weight or feel any effects. Norcodrene needs to be cycled in an 8 week on, 4 week off pattern; consumers need to be organised to follow any cycling pattern.

Overall, this diet pill could be proven to be an effective fat burner at some point in the future, but at this point the small amount of relevant clinical studies only suggests that it may aid weight loss.

The safety profile of Nocodrene is also not complete, and so only experienced diet pill users who have no serious health issues should consider this diet pill. In general, we do not recommend Nocodrene to our readers.

Watchdog Rejected Diet Pills

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See our Full Review here

Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

Have Your Say

2 comments on 'Norcodrene'

  1. I love this product. I have been taking it for about 2 weeks and it really helps with my appetite cravings. I take them in the mornings because it did have me up at night. That’s the only bad thing I can say. I feel a great burst of energy which makes working out fun to me. I haven’t gotten on the scale yet but I bet I have lost a few pounds due to me not eating so much lol. I love this product and will continue to use it.

  2. I just started taking this stuff on Monday. On the third day of taking it, my heart rate was abnormally high after a good 90 minute cardio workout. The issue was I had inadvertently drank something with high caffeine. I did have a great workout and I feel very focused, as though I was taking aderall.

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