Described as “so unique it was awarded two patents for weight loss” by the manufacturers we were compelled to see if this supplement was the real deal.
We hadn’t heard about Prevoxin until a visitor submitted a consumer report to us after seeing a TV Ad for it. Whilst we haven’t managed to see the TV Ad we have seen a few testimonials on YouTube around 4 months old who seem to be auditioning for a $1,000 and a spot on the commercial!
There is nothing like a cash reward and the promise of fame (almost 15 seconds) to motivate you to lose weight eh? Any visitors who can send us a link to the commercial we would be most appreciated 😉
Prevoxin is owned and manufactured by National Weight Loss Institute based in San Diego, California. The supplement has been trademarked on and off for at least 10 years now and the latest applicant has owned it since January 2011.
Even with some digging around online we weren’t able to find the National Weight Loss Institute website. Maybe there isn’t one? On the plus side we couldn’t find any incidences of Prevoxin scams or rip-offs reported online.
You are advised by the manufacturers to only take a maximum of 4 capsules per day, up to 2 capsules twice a day. We can only assume this is at breakfast and at lunch time as no other information is given. As each bottle contains 30 capsules taking up to 4 capsules per day means you could soon finish your supply!
The ingredient in Prevoxin is so powerful that the manufacturers claim it’s…
clinically proven to help your body produce more fat burning enzymes making it easier for you to lose pounds of unwanted weight.
What’s more, they refer to a double-blind study (no references though!) that supports the findings that….
participants who took Prevoxin lost 200% more weight than those who didn’t take Prevoxin
The manufacturer gives you 5 top reasons for why you should try Prevoxin, these are:
There’s no supplement facts or ingredient label but the FAQs page states that Prevoxin has just one active ingredient. On closer inspection on the box and bottle packing we see “100mg”, which would logically be the amount of this ingredient in each capsule.
So what’s this amazing ingredient that’s been clinically proven?
Well its 3-acetyl-7-oxo-dehydroepiandrosterone (7-KETO) is a naturally occurring metabolite (breakdown product) of the hormone dehydroepiandrosterone (DHEA) (http://en.wikipedia.org/wiki/Dehydroepiandrosterone).
Now DHEA is a very interesting and certainly a controversial hormone that is banned in many countries and only available by prescription (For example, Canada, United Kingdom and Australia). In fact it was banned by the FDA in the US up until 1994 for its potential for abuse and the high risk of serious side effects.
As 7-Keto DHEA is a steroid produced by metabolism of DHEA and as such the World Anti-Doping Agency lists it as a prohibited anabolic agent. (http://list.wada-ama.org/list/s1-anabolic-agents/)
The most important point to realise with Prevoxin is that it’s only legal to buy in some countries that don’t require a prescription for DHEA based supplements.
The manufacturer states that no known side effects from taking Prevoxin.
There is however concerns over the safety of DHEA when taking dosages higher than 50-100mg for a long-period of time (see Medline Plus for more information – http://www.nlm.nih.gov/medlineplus/druginfo/natural/331.html#Safety).
A number of organisations have expressed concern over DHEA and its derivatives, the MayoClinic had this to say…
no studies on the long-term effects of DHEA have been conducted. DHEA can cause higher than normal levels of androgens and estrogens in the body, and theoretically may increase the risk of prostate, breast, ovarian, and other hormone-sensitive cancers. Therefore, it is not recommended for regular use without supervision by a licensed health professional.
The Advisory Council on the Misuse of Drugs (ACMD) have reported their concerns more recently in November 2011…
The ACMD has carefully considered the potential physical and social harms of 7- hydroxy DHEA and 7-keto DHEA and advises that these are commensurate with other Class C drugs.
Caution: If you’re a pregnant women or a nursing mother then you should avoid taking this supplement. Anyone taking prescription medication should seek medical advice before taking this supplement.
No customer testimonials are shown on the official site and we struggled to find any independent ones apart from the two YouTube videos. Considering the video testimonials are competing to win the $1,000 and appearance on a Prevoxin commercial it’s difficult to see these as independent reviews!
Although the use of the parent hormone DHEA is linked to increased fat metabolism studies on humans are less conclusive. A number of studies have shown little to no changes in total weight and body fat mass even when taking a daily dose of 1,600mg of DHEA (http://www.ncbi.nlm.nih.gov/pubmed/2143499).
Whilst there is a fair amount of research about DHEA there is without doubt there are far fewer studies on 7-Keto DHEA, so we initially not too optimistic about finding conclusive data to support the manufacturers’ claims.
Douglas S. Kaiman and colleagues published a study in July 2000 that looked at 30 overweight but healthy individuals dividing them into 2 random groups of 15 to make a “control” and “test” group. The “test” subjects received 200mg of 7-Keto DHEA and the “control” group a placebo. After 8 weeks they found the “test” group lost on average 2.88kg compared to the placebo group who lost just 0.97kg. This is where the manufacturer most likely got the 3 times more weight loss claim!
You can find the published study here: http://www.sciencedirect.com/science/article/pii/S0011393X00800260
It’s worth noting that ALL subjects in the trial followed a strict diet of 1,800Kcal per day and performed 60 minutes of cross training 3 times per week through the study.
To consume enough 7-Keto DHEA as seen in this study you would need to take at least 2 Prevoxin capsules per day.
7-keto WILL NOT promote weight loss without a healthful diet and regular exercise!
The claims made by Prevoxin that it works to boost metabolism by stimulating the production of fat burning enzymes may well be the case but the evidence is certainly not conclusive!
In fact a number of sources state there is insufficient scientific evidence to support its use as a weight-loss aid, muscle-builder, immune stimulant, or for any other clinical use.
Available directly from the official website, Prevoxin is currently offering 2 bottles for the price of one, which also includes a free bottle of LipoBurn for just $29.95.
So what is LipoBurn?
There are a number of similar named diet supplements however we could find little information about this one. In fact only a few sentences on the Prevoxin website say that it’s suppose to promote an increased metabolism and boost energy levels. The ingredients are revealed (Green Tea, Guarana, Caffeine, Oolong Tea, Kola-nut, Cayenne Fruit, Platycodon Grandiflorum and Vitamins B6 and B12) but no amounts are listed.
We can’t be 100% sure, but it’s likely that LipoBurn is a cheap diet pill and there is no evidence that this works. It’s simply added to make purchasing Prevoxin seem an even better deal!
Consumer Alert: One bottle of Prevoxin contains 30 capsules and so if you take up to 4 capsules per day, one bottle will only last just over a week. This means that two bottles will last just 15 days!
After looking through the “terms and conditions” we found that a 30-day money-back guarantee is available less shipping and handling fee. It’s not clear what the handling fee is though.
The guarantee/returns policy only applies to online and TV purchases made directly from Prevoxin.
We were initially put off by the lack of any real in-depth information about Prevoxin available. After some digging into both DHEA and 7-Keto, and the fact that these substances are banned in many countries, a few alarm bells were triggered. We couldn’t help but ask: just how safe is it?
As we progressed through our review our concerns grew. The lack of independent testimonials from consumers, missing references to clinical trials and lack of any real information about the company behind the product caused us concern.
What appears to be a very cost effective supplement may work out expensive depending on the number of capsules taken daily. If you do decide to take up to 4 capsules per day you will quickly run out of supply, which means that you could need 4 bottles to just last one month!
In the end though there were just too many concerns that mean we are going to reject Prevoxin.
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Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.