Thermo Heat

Thermo Heat is a powerful looking fat burner that makers Advanced Molecule Labs describe as The Most Advanced Thermogenic Ever Developed. This maximum strength supplement may even improve your mood as well. So will it help your weight loss too and more importantly is it safe?

We take an in depth look at Thermo Heat to find out.

Thermo Heat Pros

  • Will probably help short-term weight loss
  • Some of the minor ingredients such as tangerine peel look good

Thermo Heat Cons

  • May cause dangerous side effects
  • Putting the body into permanent flight or fight response, does not lead to long-term weight loss
  • Very little customer feedback
Watchdog Rejected Diet Pills
thermo heat

Thermo Heat Review

Thermo Heat Facts

  • Made by US company, Advanced Molecular Labs
  • Available in 2 bottle sizes. 60 or 120 capsules
  • Contains synephrine and yohimbine – two stimulants recognised as dangerous

Thermo Heat is a fat burner, which contains a lot of ingredients! And according to the product information, this combination will not only help you burn fat it will help you manage your appetite, boost alertness and enhance mood and energy levels too.

Most of these effects will be down to stimulants contained in the formula.

There is 250mg of caffeine per serving, plus Advantra Z – a branded citrus Aurantium compound. Citrus Aurantium also known as bitter orange contains synephrine – chemically related to amphetamines and is well known for its stimulant effects. It raises adrenaline levels and increases heart rate and blood pressure levels so will not be suitable for everyone.

Other stimulants include amino acid L tyrosine – known for enhancing alertness and keeping you awake and yohimbine – a plant stimulant known as an androgenic – another part of the formula that increases adrenaline.

There are also ingredients, which may affect mood and metabolism. These include Velvet Bean – a plant extract that grows in Africa and contains L DOPA – a precursor to dopamine and adrenaline. In its natural state, it is sometimes smoked for recreational purposes.

In fact, there are too many ingredients to explain each one of them here. Some are quite unusual – such as a plant called Holy Basil and the grisly sounding Ox Bile extract, which is believed to help regulate a healthy metabolism.

Other ingredients like Green coffee bean and raspberry ketones are more mainstream and are included because of their well known effects upon weight gain. Although the claims for these particular ingredients have been widely over stated by the diet industry, they remain popular.

We have concerns about the size of this ingredient list and some of the components.

After all, the higher the number of ingredients, the greater the risk of side effects and we can already see that there may be health issues with this supplement. There is a long list of warnings provided in the product information about side effects and who should not use this supplement.

The Thermo Heat formula is under a proprietary blend so apart from the caffeine, none of the quantities are provided. This makes it impossible to gauge the true strength and effects of this supplement.

That said the sum total of active ingredients per serving adds up to a whopping 1293mg so it is likely that you will notice taking this supplement.

How to Take Thermo Heat

Start with 2 capsules for the first three days (1 in the morning and 1 in the afternoon).

If well tolerated, then you can increase the amount taken to 2 Thermo Heat capsules in the morning and 2 Thermo Heat capsules in the afternoon.

Do Not Exceed 4 Thermo Heat Capsules Per Day. Do not take within 6 hours of sleep. For optimum results, Thermo Heat should not be taken with meals. Consume at least 30 minutes before a meal.

For those individuals with digestive sensitivities to spices, it is recommended to consume product after meals for greater tolerance.

Thermo Heat is best used as part of a diet and exercise program.

Thermo Heat is made and marketed by Advanced Molecular Labs an American supplements company that produce four supplements. Thermo Heat and Thermo Heat Night Time, which you can take in combination with thermo heat for 24 hours fat burning.

There is also a Pre Work Out Supplement, called PreWorkout and Post WorkOut designed to replace lost minerals and salts.
We have not covered AML supplements before.

Thermo Heat Concerns:

  • Strong risk of potentially very dangerous side effects
  • Has this formula ever been tested? It all looks a bit pick and mix to us
  • It may cause some initial weight loss but evidence shows that losing weight with stimulants does not lead to long-term weight loss

What Does Thermo Heat Claim To Do?

There are six major claims to this supplement:


    ignites your body’s fat burning by switching on the metabolically inactive white adipose tissue (WAT) so that it acts more similar to the most proficient thermogenic tissue in the body–brown adipose tissue (BAT) or brown fat.

    All humans and mammals have two types of fat: white adipose tissue and brown adipose tissue. Brown adipose tissue (BAT) is the layer of fat cells that is important for keeping you warm.

  • THERMO HEAT SUPPORTS HEALTHY THYROID FUNCTION. According to AML, it does this by maintaining thyroid efficiency even when you are on a calorie-controlled diet.
  • THERMO HEAT SAFELY STIMULATES THE BETA-3-ADRENERGIC SYSTEM, A KEY PATHWAY FOR FAT BURNING. This means it stimulate the adrenaline levels, putting your body into flight or fight mode.
  • THERMO HEAT CONTAINS NORADRENALINE AND DOPAMINE ACTIVATORS. Some of the ingredients contained in the formula are believed to help the production of these hormones although more evidence is required.
  • THERMO HEAT ENERGIZES WITHOUT OVER-STIMULATING. We question this claim. This diet pill looks strong and probably will cause a jittery effect at least for some users.
  • THERMO HEAT HELPS MANAGE YOUR APPETITE. Stimulants can reduce appetite by making you feel too on edge to eat so it may help weight loss in this way. According to AML, Thermo Heat is “The Most Revolutionary Fat Burner Ever Developed!”

So What Is Thermo Heat and What Are The Ingredients?

  • Advantra-Z® (Bitter Orange Fruit Extract – standardized for synephrine alkaloids): This trademarked supplement contains citrus extract chemicals synephrine, octopamine, and N-Methyltyramine plus Tyramine and Hordenine derived from barley. These are described as Sympathomimetic agents, which mean that they affect the nervous system and mimic the effects of the flight or fight response. As everybody knows from experience, this response raises the heart rate, causes sweating and other stress related symptoms. It also decreases the appetite – one reason why Sympathomimetic agents are used in diet pills.
  • N-Acetyl-L-Tyrosine: This amino acid is believed to stimulate brain chemicals serotonin and dopamine and is sometimes taken to treat depression and ADD. Research suggests that taking 150mg will improve alertness for around three hours.
  • Caffeine (250 mg): Most diet supplements contain caffeine and it is ideal for giving you a quick energy boost. It can increase the speed of the metabolism and help fat burning but the effects are often short lived as you become accustomed to use. Amount contained here roughly the equivalent of 5 cups of instant coffee.
  • Holy Basil: Indian plant believed to lower blood sugar. It is also claimed for a variety of conditions including anxiety, stress, ringworm and as cancer treatment. Requires further evidence.
  • Japanese Sapphora (Sapphora Japonica) Extract (containing Kaempferol): Kaempferol is a natural flavenol a type of antioxidant that is currently undergoing testing as a treatment for some type of cancers. Kaempferol is also present in ordinary foodstuffs including apples and potatoes. Believed to reverse insulin resistance too but all testing of this ingredient is at a very early stage.
  • Cayenne Pepper Fruit Extract: When taken in very high quantities, some research has indicated that high levels of capsaicoinds, the compound that causes the fiery sensation of cayenne, increases the metabolism and promotes fat burning.
  • Velvet Bean (Mucuna pruriens): This climbing plant is native to Africa and Asia. It contains L DOPA (L-3, 4-dihydroxyphenylalanine) a precursor to dopamine and adrenaline. It also contains minor amounts of serotonin and nicotine. Velvet bean is sometimes smoked for recreational purposes.
  • Ox Bile Extract (containing Bile Acids): It sounds disgusting but in some cultures, ox bile is used as a medicine for complaints including gallstones and constipation. At low levels this ingredient is “generally recognised as safe” (GRAS) by the FDA. It is believed to improve the metabolism.
  • Ginger Root Extract (5% gingerols): May be effective as a treatment for digestive issues such as nausea. Gingerols – the active compound in ginger may have medical benefits but requires further testing.
  • Wakame Seaweed ( (containing fucoxanthin): Animal testing suggests that fucoxanthin derived from Wakame (Undaria Pinnatifida) may reduce cholesterol levels but as yet no evidence it will do the same for humans.
  • Forskohlii (Coleus Forskohlii) Root Extract (10% forskolin): Forskolin is a chemical derived from a natural plant called Coleus Forskohlii and some limited clinical testing suggests it may increase testosterone levels.
  • Naringin: This chemical is derived from grapefruit peel and is believed to create a weight loss effect due to its effects upon the metabolism. Including more grapefruit into your diet is a good way of promoting weight loss but contents here unknown. Interacts with medication.
  • Hesperidins: Substance present in the skin of citrus fruits believed to play a role in plant defence. May have an application in medicine but requires investigation.
  • Black Pepper Fruit Extract (95% Piperine): Black pepper extract is believed to increase the absorption of other ingredients so may make them more effective.
  • Tangerine Peel Extract: Believed to lower cholesterol. A joint study by the U.S. Department of Agriculture and a Canadian research firm, published in the April 2004 issue of the “Journal of Agricultural and Food Chemistry,” cited the cholesterol-lowering properties of tangerine peel.
  • Olive Leaf Extract (15% Oleuropein): We all know olive oil is good for health and it may be effective at treating flu, viral infections and bacterial infections. Does not appear to have much relevance here but a healthy and safe ingredient.
  • Green Coffee Bean Extract (45% chlorogenic acids): Much touted weight loss ingredient that suffers from a lack of evidence that it will work in the way as described. It is supposed to help block fat but most claims are based on a now disgraced clinical trial carried out in India. To find out more about green coffee see our Watchdog investigation.
  • Raspberry Ketones: Plant phenols found in the skin of raspberries and believed to have semi miraculous weight loss benefits. However, this much-touted ingredient lacks real evidence and has mainly been tested on rodents.
  • Yohimbe Bark Extract: This natural stimulant is believed to have aphrodisiac effects making it popular in treatments for erectile dysfunction. However, side effects are a major concern and include changes to blood pressure, increases in heart rate and even heart attack and seizure.
  • Cassia (Cinnamon) bark extract: There has been a lot of clinical testing carried out on cinnamon bark but the only conclusion is that results are inconclusive. It may be effective in reducing cholesterol levels if taken at very high levels.
  • Turmeric Root Extract (95% curcuminoids): Familiar to curry lovers, this bright yellow spice is also medicinal and may be effective for treatment of osteoarthritis. However, there does not appear to be a proven application for weight loss.

So What Does All This Mean?

Thermo Heat looks like a pick and mix of ingredients that the makers have put together because on paper these are supposed to cause specific effects.

Some ingredients have been included to reduce cholesterol. We love tangerine peel – it seems to be effective but most of the other ingredients lack any real evidence. Others like Forskolin are supposed to increase testosterone, some like velvet bean and cayenne may increase serotonin and improve mood.

However, the most noticeable effect will be caused by the high levels of stimulants and sympathomimetic agents – ingredients that directly affect your nervous system and adrenaline levels.

We question the sense of putting your body into stress mode by increasing adrenaline levels. It may help you lose weight short term by decreasing your appetite and you will probably experience an energy buzz but this comes with some serious health concerns.

Does Thermo Heat Have Any Side Effects?

Thermo Heat can cause side effects. According to the product information, you are advised to immediately discontinue if you experience; rapid heartbeat, dizziness, severe headaches or shortness of breath.

Other side effects may include:

  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Sweating
  • Fainting
  • Irritability
  • Anxiety
  • Jitteriness
  • Insomnia
  • Elevated blood pressure
  • Increased heart rate
  • Increased risk of stroke/ heart attack

The product information provides a comprehensive list of cautions.


Not for use by persons under the age of 18.

Do not use if pregnant or nursing.

Do not exceed recommended dosage.

This product contains 250 mg of caffeine. Caffeine sensitive individuals and others sensitive to stimulants should not consume this product.

Do not consume synephrine, caffeine or thyroid-boosting compounds from other sources, including but not limited to, Monoamine Oxidase Inhibitors (MAOI), anti-depressants, allergy, asthma, cough or cold and weight control drugs, or products containing phenylephrine, ephedrine, pseudoephedrine or other stimulants while taking this product.

Consult your physician prior to use if you are consuming prescription drugs, over the counter products, or other dietary supplement products, and if you have a medical condition or family history of, including but not limited to heart, liver, kidney, or thyroid disease, depression, anxiety or psychiatric disorders, seizure disorder, difficulty urinating, diabetes, cardiovascular disease, stroke, high blood pressure, cardiac arrhythmia, recurrent headaches, enlarged prostate or glaucoma.

We also advise you to avoid this supplement if you are a competition athlete because it could see you disqualified for doping.

Bitter orange supplements are banned by many sports bodies including the National Collegiate Athletic Association (NCAA).

Any Reviews From Customers?

There is very little available feedback for Thermo heat. One customer reported,

Fair warning, this stuff hurts your stomach. You will feel a bit of discomfort until you eat 30 min after taking them on an empty stomach, but they do work. I’ve been taking them for a week now and do see a noticeable difference in body fat %, as far as increased energy though, I haven’t noticed any.

We have found some detailed blog reviews of Thermo Heat. Comments included,

These fat burners will make you sweat a lot and if you like the feeling of an increased heart-rate, you’ll love these. If you’re not fond of this feeling, I’d advise you to stay far away from this product.

Another liked the enhanced energy and the appetite suppressing effect but complained of feeling wired and nauseous. She also had an issue with the capsules.

I felt like my throat was on fire – and it took over an hour (and drinking a ton of water) to feel better.

This reviewer did experience weight loss.

So Does Thermo Heat Work?

Stimulants that directly affect adrenaline levels and the central nervous system are called Sympathomimetic agents.

These are well known for reducing the appetite and food cravings, so yes Thermo heat will probably help short-term weight loss. However, according to the Journal of Obesity,

Sympathomimetic agents have a poor history of long-term success in the treatment of obesity.

This detailed study examined Advantra Z – a principle ingredient in Thermo heat. The conclusion was that the risks to heart health were very high. The conclusion was that these type of stimulants,

possess an unreasonable cardiovascular toxic potential that emerges when the drugs are applied to a broad spectrum of the population, many of whom may have unrecognized risk factors.

Where Can I Buy Thermo Heat?

Thermo Heat is not widely available in the shops but you can buy online direct from the AML website. One bottle of 60 capsules (15 – 30 days supply) costs $59.95. One bottle of 120 capsules ( 30 – 60 days supply) costs $79.95. Flat rate shipping to US addresses costs an additional $5.95.

You can also buy Thermo Heat from various sellers via Amazon USA. 60 capsules costs $36.99, 120 capsules costs $52.99. Prices and shipping varies depending on seller.

What About A Guarantee

No guarantee is offered.

Watchdog Verdict

Thermo Heat will probably help you achieve some short-term weight loss. It contains a lot of different types of stimulants so you will probably experience a loss of appetite as well as a chemically boosted energy rush.

The Journal of Obesity has mentioned one of the principle ingredients Advantra Z as posing an unreasonable risk to heart health and even if you feel that you are healthy, you may have unrecognised risk factors which could make this supplement dangerous. That is before we take the high levels of caffeine and added risk of Yohimbine into consideration.

In addition, there are numerous other ingredients contained in this supplement and although some of these look interesting, will you really notice any other effects other than this potentially toxic cocktail of stimulants? It is possible that this combination will cause added problems too.

The truth is we just don’t know and more worryingly, nor do the makers AML. Many of the ingredients lack clinical testing for safety or interactions, so if you decide to take this, don’t say we didn’t warn you!

There is no way we would recommend such a dangerous looking supplement so this is an easy decision. We reject Thermo Heat.

Watchdog Rejected Diet Pills
Thermo Heat

2 out of 5
Thermo Heat
  • Effectiveness
  • Safety
  • Price / Guarantee

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See our Full Review here

Disclaimer: Our reviews and investigations are based on extensive research from the information publicly available to us and consumers at the time of first publishing the post. Information is based on our personal opinion and whilst we endeavour to ensure information is up-to-date, manufacturers do from time to time change their products and future research may disagree with our findings. If you feel any of the information is inaccurate, please contact us and we will review the information provided.

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1 comment on 'Thermo Heat'

  1. I figured I would share my experience with this supplement to date.
    Usage Duration: 34 days, taking 4 capsules a day.
    Current workout routine: 5-6 days of weight training with 15-20 min of HITT prior to the workout.
    Diet: Following a strict macronutrient diet for my goals.

    Set up: Prior to starting this pill i was following the same workout regimen and diet for about 3 weeks. Upon starting to the pill I noticed a decrease in appetite, a slight bump in energy and focus. I maintained the same caloric intake pre/post pill.
    Results thus far: Since starting the pill i’ve noticed a 3% decrease in body fat (down from 10%). As far as weight I don’t keep track of a scale number as body fat% is my goal i’d estimate down about 6lbs. Due to my diet the results can mostly be attributed to that, however I did notice results more rapidly after starting the pill. Now for the cons.. much like many reviews state, this product will upset your stomach if taken without food. I’m not talking slightly upset, but upset to the point you don’t feel like moving until it passes (which it does in about 30 min). If you take the product with food this is not an issue. Next con, elevated heart rate and blood pressure. In my specific case this product caused my blood pressure to read in the prehypertension range ( I know this because i checked it pre pill and post pill as my gym has a monitor). The last con, this pill makes you sweat. I naturally sweat a little above the average person, but by the time i am finished with my workout i am drenched head to toe. This isn’t a con for some people, but i will advise stay hydrated if you use this pill. I don’t believe 30 days is enough time to have accurate results that can be statistically significant, therefore i purchased another month and will continue out to 60 days.

    To summarize:
    Pros: Fat loss, Energy, appetite suppressant, some focus.
    Cons: Upset Stomach (if you don’t eat, arguably the most apparent and will make you want to quit after pill 1), elevated heart rate, elevated blood pressure, excess sweating.

    I hope this helps.